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Cell Signal Transduction Research Antibodies
TAFI Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight48412Da
Protein NameCarboxypeptidase B2
Human Gene Id1361
Human Swiss Prot NoQ96IY4
Mouse Swiss Prot NoQ9JHH6
SpecificityTAFI Polyclonal Antibody detects endogenous levels of TAFI protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCPB2; Carboxypeptidase B2; Carboxypeptidase U; CPU; Plasma carboxypeptidase B; pCPB; Thrombin-activable fibrinolysis inhibitor; TAFI
Observed Band(KD)48
Functioncatalytic activity:Release of C-terminal Arg and Lys from a polypeptide.,cofactor:Binds 1 zinc ion per subunit.,function:Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities.,similarity:Belongs to the peptidase M14 family.,tissue specificity:Plasma; synthesized in the liver.,
Subcellular Locationextracellular space,cell,extracellular exosome,
ExpressionLiver,Plasma,Skeletal muscle,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human CPB2. AA range:321-370
Gene NameCPB2
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Backgroundcarboxypeptidase B2(CPB2) Homo sapiens Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],
Conjugated Antibody
This product is also available conjugated. Format: E20-74533-Conjugate. Price: $485 / Size: 100μl.
E20-74533-FITC$485 / 100μlE20-74533-Biotin$485 / 100μlE20-74533-HRP$485 / 100μlE20-74533-AP$485 / 100μlE20-74533-AF350$485 / 100μlE20-74533-AF405M$485 / 100μlE20-74533-AF488$485 / 100μlE20-74533-AF514$485 / 100μlE20-74533-AF532$485 / 100μlE20-74533-AF555$485 / 100μlE20-74533-AF568$485 / 100μlE20-74533-AF405S$485 / 100μlE20-74533-AF405L$485 / 100μlE20-74533-AF546$485 / 100μlE20-74533-AF594$485 / 100μlE20-74533-AF610$485 / 100μlE20-74533-AF635$485 / 100μlE20-74533-AF647$485 / 100μlE20-74533-AF680$485 / 100μlE20-74533-AF700$485 / 100μlE20-74533-AF750$485 / 100μlE20-74533-AF790$485 / 100μlE20-74533-APC$485 / 100μlE20-74533-PE$485 / 100μlE20-74533-Cy3$485 / 100μlE20-74533-Cy5$485 / 100μlE20-74533-Cy5.5$485 / 100μlE20-74533-Cy7$485 / 100μlE20-74533-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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