TAF II p68 Polyclonal Antibody

Name: TAF II p68 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-74530
Price: 225 USD
Availability: InStock

E20-74530Cite ID: EN0054663Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight61830 DaObserved Band:62 KD

Protein NameTATA-binding protein-associated factor 2N

Human Gene Id8148

Human Swiss Prot NoQ92804

SpecificityTAF II p68 Polyclonal Antibody detects endogenous levels of TAF II p68 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameTAF15; RBP56; TAF2N; TATA-binding protein-associated factor 2N; 68 kDa TATA-binding protein-associated factor; TAF(II)68; TAFII68; RNA-binding protein 56

Functiondisease:A chromosomal aberration involving TAF15/TAF2N is found in a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with NR4A3.,function:RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II).,PTM:Arg-206 is dimethylated, probably to asymmetric dimethylarginine.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the RRM TET family.,similarity:Contains 1 RanBP2-type zinc finger.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Belongs to the RNA polymerase II (Pol II) transcriptional multiprotein complex, together with the TATA-binding protein (TBP) and other TBP-associated factors (TAF(II)s). Binds SF1.,tissue specificity:Ubiquitous. Observed in all fetal and adult ti

Subcellular LocationNucleus . Cytoplasm . Shuttles from the nucleus to the cytoplasm.

ExpressionUbiquitous. Observed in all fetal and adult tissues.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human TAF15. AA range:351-400

Gene NameTAF15

DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

BackgroundTATA-box binding protein associated factor 15(TAF15) Homo sapiens This gene encodes a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-74530-Conjugate. Price: $485 / Size: 100μl.

E20-74530-FITC$485 / 100μlE20-74530-Biotin$485 / 100μlE20-74530-HRP$485 / 100μlE20-74530-AP$485 / 100μlE20-74530-AF350$485 / 100μlE20-74530-AF405M$485 / 100μlE20-74530-AF488$485 / 100μlE20-74530-AF514$485 / 100μlE20-74530-AF532$485 / 100μlE20-74530-AF555$485 / 100μlE20-74530-AF568$485 / 100μlE20-74530-AF405S$485 / 100μlE20-74530-AF405L$485 / 100μlE20-74530-AF546$485 / 100μlE20-74530-AF594$485 / 100μlE20-74530-AF610$485 / 100μlE20-74530-AF635$485 / 100μlE20-74530-AF647$485 / 100μlE20-74530-AF680$485 / 100μlE20-74530-AF700$485 / 100μlE20-74530-AF750$485 / 100μlE20-74530-AF790$485 / 100μlE20-74530-APC$485 / 100μlE20-74530-PE$485 / 100μlE20-74530-Cy3$485 / 100μlE20-74530-Cy5$485 / 100μlE20-74530-Cy5.5$485 / 100μlE20-74530-Cy7$485 / 100μlE20-74530-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.