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Cell Signal Transduction Research Antibodies
TADA2L Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight(Da):51496
Protein NameTranscriptional adapter 2-alpha
Human Gene Id6871
Human Swiss Prot NoO75478
Mouse Gene Id217031
Mouse Swiss Prot NoQ8CHV6
Rat Gene Id360581
Rat Swiss Prot NoQ6AYE3
SpecificityTADA2L Polyclonal Antibody detects endogenous levels of TADA2L protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTADA2A; TADA2L; KL04P; Transcriptional adapter 2-alpha; Transcriptional adapter 2-like; ADA2-like protein
Observed Band(KD)47
Functionfunction:Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling (By similarity). Required for the function of some acidic activation domains, which activate transcription from a distant site.,similarity:Contains 1 SANT domain.,similarity:Contains 1 SWIRM domain.,subunit:Interacts with GCN5 and NR3C1. Associated with the P/CAF protein in the PCAF complex. Component of the PCAF complex, at least composed of TADA2L/ADA2, TADA3L/ADA3, TAF5L/PAF65-beta, TAF6L/PAF65-alpha, TAF10/TAFII30, TAF12/TAFII20, TAF9/TAFII31 and TRRAP.,tissue specificity:Expressed in all tissues, but most abundantly in testis.,
Subcellular LocationNucleus . Chromosome .
ExpressionExpressed in all tissues, but most abundantly in testis.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human ADA2L. AA range:206-255
Gene NameTADA2A
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundtranscriptional adaptor 2A(TADA2A) Homo sapiens Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Oct 2009],
Conjugated Antibody
This product is also available conjugated. Format: E20-74524-Conjugate. Price: $485 / Size: 100μl.
E20-74524-FITC$485 / 100μlE20-74524-Biotin$485 / 100μlE20-74524-HRP$485 / 100μlE20-74524-AP$485 / 100μlE20-74524-AF350$485 / 100μlE20-74524-AF405M$485 / 100μlE20-74524-AF488$485 / 100μlE20-74524-AF514$485 / 100μlE20-74524-AF532$485 / 100μlE20-74524-AF555$485 / 100μlE20-74524-AF568$485 / 100μlE20-74524-AF405S$485 / 100μlE20-74524-AF405L$485 / 100μlE20-74524-AF546$485 / 100μlE20-74524-AF594$485 / 100μlE20-74524-AF610$485 / 100μlE20-74524-AF635$485 / 100μlE20-74524-AF647$485 / 100μlE20-74524-AF680$485 / 100μlE20-74524-AF700$485 / 100μlE20-74524-AF750$485 / 100μlE20-74524-AF790$485 / 100μlE20-74524-APC$485 / 100μlE20-74524-PE$485 / 100μlE20-74524-Cy3$485 / 100μlE20-74524-Cy5$485 / 100μlE20-74524-Cy5.5$485 / 100μlE20-74524-Cy7$485 / 100μlE20-74524-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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