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Cell Signal Transduction Research Antibodies
TACC3 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight90360 DaObserved Band:80 KD
Protein NameTransforming acidic coiled-coil-containing protein 3
Human Gene Id10460
Human Swiss Prot NoQ9Y6A5
Mouse Swiss Prot NoQ9JJ11
SpecificityTACC3 Polyclonal Antibody detects endogenous levels of TACC3 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTACC3; ERIC1; Transforming acidic coiled-coil-containing protein 3; ERIC-1
Functionfunction:Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). May be involved in the control of cell growth and differentiation. May contribute to cancer.,induction:Up-regulated in various cancer cell lines.,similarity:Belongs to the TACC family.,subunit:Interacts with microtubules. Interacts with CCDC100/CEP120. The coiled coil C-terminus region interacts with AH receptor nuclear translocator protein (ARNT) and ARNT2 (By similarity). Interacts with GCN5L2 and PCAF.,
Subcellular LocationCytoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, spindle pole . In complex with CKAP5 localized to microtubule plus-ends in mitosis and interphase. In complex with CKAP5 and clathrin localized to inter-microtubule bridges in mitotic spindles. .
ExpressionEpithelium,PCR rescued clones,Skin,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human TACC3. AA range:789-838
Gene NameTACC3
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Backgroundtransforming acidic coiled-coil containing protein 3(TACC3) Homo sapiens This gene encodes a member of the transforming acidic colied-coil protein family. The encoded protein is a motor spindle protein that may play a role in stabilization of the mitotic spindle. This protein may also play a role in growth a differentiation of certain cancer cells. [provided by RefSeq, Nov 2011],
Conjugated Antibody
This product is also available conjugated. Format: E20-74522-Conjugate. Price: $485 / Size: 100μl.
E20-74522-FITC$485 / 100μlE20-74522-Biotin$485 / 100μlE20-74522-HRP$485 / 100μlE20-74522-AP$485 / 100μlE20-74522-AF350$485 / 100μlE20-74522-AF405M$485 / 100μlE20-74522-AF488$485 / 100μlE20-74522-AF514$485 / 100μlE20-74522-AF532$485 / 100μlE20-74522-AF555$485 / 100μlE20-74522-AF568$485 / 100μlE20-74522-AF405S$485 / 100μlE20-74522-AF405L$485 / 100μlE20-74522-AF546$485 / 100μlE20-74522-AF594$485 / 100μlE20-74522-AF610$485 / 100μlE20-74522-AF635$485 / 100μlE20-74522-AF647$485 / 100μlE20-74522-AF680$485 / 100μlE20-74522-AF700$485 / 100μlE20-74522-AF750$485 / 100μlE20-74522-AF790$485 / 100μlE20-74522-APC$485 / 100μlE20-74522-PE$485 / 100μlE20-74522-Cy3$485 / 100μlE20-74522-Cy5$485 / 100μlE20-74522-Cy5.5$485 / 100μlE20-74522-Cy7$485 / 100μlE20-74522-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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