Product Information
Molecular Weight63626 DaObserved Band:64 KD
Protein NameTRAF3-interacting JNK-activating modulator
Human Gene Id80342
Human Swiss Prot NoQ9Y228
Mouse Gene Id215243
Mouse Swiss Prot NoQ8C0G2
SpecificityT3JAM Polyclonal Antibody detects endogenous levels of T3JAM protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameTRAF3IP3; T3JAM; TRAF3-interacting JNK-activating modulator; TRAF3-interacting protein 3
Functionfunction:May function as an adapter molecule that regulates TRAF3-mediated JNK activation.,subunit:Binds to the isoleucine zipper of TRAF3 via its coiled-coil domain.,
Subcellular LocationCell membrane . Golgi apparatus membrane ; Single-pass type IV membrane protein . Lysosome membrane . Mitochondrion outer membrane . Accumulates on the mitochondria after virus infection. .
ExpressionBlood,Lung adenocarcinoma,
BackgroundTRAF3 interacting protein 3(TRAF3IP3) Homo sapiens The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],