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T2R7 Polyclonal Antibody
Datasheet
Catalog Number:
E20-74515Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human TAS2R7. AA range:47-96Source:
Polyclonal, RabbitGene Name:
TAS2R7Dilution:
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
- Immunofluorescence analysis of MCF7 cells, using TAS2R7 Antibody. The picture on the right is blocked with the synthesized peptide.
Background:
taste 2 receptor member 7(TAS2R7) Homo sapiens This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2008],Protein Name:
Taste receptor type 2 member 7Human Gene Id:
50837Human Swiss Prot No:
Q9NYW3Mouse Swiss Prot No:
P59530Specificity:
T2R7 Polyclonal Antibody detects endogenous levels of T2R7 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
TAS2R7; Taste receptor type 2 member 7; T2R7; Taste receptor family B member 4; TRB4MolecularWeight(Da):
36550Observed Band(KD):
36Function:
function:Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.,miscellaneous:Several bitter taste receptors are expressed in a single taste receptor cell.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.,Subcellular Location:
plasma membrane,integral component of membrane,
- Western blot analysis of lysates from K562, LOVO, and A549 cells, using TAS2R7 Antibody. The lane on the right is blocked with the synthesized peptide.
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