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T2R3 Polyclonal Antibody
Datasheet
Catalog Number:
E20-74508Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human TAS2R3. AA range:140-189Source:
Polyclonal, RabbitGene Name:
TAS2R3Dilution:
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
- Immunofluorescence analysis of A549 cells, using TAS2R3 Antibody. The picture on the right is blocked with the synthesized peptide.
Background:
taste 2 receptor member 3(TAS2R3) Homo sapiens This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. These apparently intronless taste receptor genes encode a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008],Protein Name:
Taste receptor type 2 member 3Human Gene Id:
50831Human Swiss Prot No:
Q9NYW6Mouse Swiss Prot No:
Q7TQA7Specificity:
T2R3 Polyclonal Antibody detects endogenous levels of T2R3 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
TAS2R3; Taste receptor type 2 member 3; T2R3MolecularWeight(Da):
35915Function:
function:Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.,miscellaneous:Several bitter taste receptors are expressed in a single taste receptor cell.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells. Expressed in the antrum and fundus (part of the stomach), duodenum and in gastric endocrine cells.,Subcellular Location:
plasma membrane,integral component of membrane,
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