SYP Polyclonal Antibody

Name: SYP Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-74500
Price: 225 USD
Availability: InStock

E20-74500Cite ID: EN0054633Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight33845 DaObserved Band:38 KD

Protein NameSynaptophysin

Human Gene Id6855

Human Swiss Prot NoP08247

Mouse Gene Id20977

Mouse Swiss Prot NoQ62277

Rat Gene Id24804

Rat Swiss Prot NoP07825

SpecificitySYP Polyclonal Antibody detects endogenous levels of SYP protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameSYP; Synaptophysin; Major synaptic vesicle protein p38

Functiondomain:The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.,function:Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.,online information:Synaptophysin entry,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the synaptophysin/synaptobrevin family.,similarity:Contains 1 MARVEL domain.,subunit:Homohexamer or homotetramer.,tissue specificity:Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.,

Subcellular LocationCytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Multi-pass membrane protein . Cell junction, synapse, synaptosome .

ExpressionExpressed in the brain, with expression in the hippocampus, the neuropil in the dentate gyrus, where expression is higher in the outer half of the molecular layer than in the inner half, and in the neuropil of CA4 and CA3 (PubMed:8838578). Expressed in the putamen (at protein level) (PubMed:17296554).

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human Synaptophysin. AA range:101-150

Gene NameSYP

DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Backgroundsynaptophysin(SYP) Homo sapiens This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-74500-Conjugate. Price: $485 / Size: 100μl.

E20-74500-FITC$485 / 100μlE20-74500-Biotin$485 / 100μlE20-74500-HRP$485 / 100μlE20-74500-AP$485 / 100μlE20-74500-AF350$485 / 100μlE20-74500-AF405M$485 / 100μlE20-74500-AF488$485 / 100μlE20-74500-AF514$485 / 100μlE20-74500-AF532$485 / 100μlE20-74500-AF555$485 / 100μlE20-74500-AF568$485 / 100μlE20-74500-AF405S$485 / 100μlE20-74500-AF405L$485 / 100μlE20-74500-AF546$485 / 100μlE20-74500-AF594$485 / 100μlE20-74500-AF610$485 / 100μlE20-74500-AF635$485 / 100μlE20-74500-AF647$485 / 100μlE20-74500-AF680$485 / 100μlE20-74500-AF700$485 / 100μlE20-74500-AF750$485 / 100μlE20-74500-AF790$485 / 100μlE20-74500-APC$485 / 100μlE20-74500-PE$485 / 100μlE20-74500-Cy3$485 / 100μlE20-74500-Cy5$485 / 100μlE20-74500-Cy5.5$485 / 100μlE20-74500-Cy7$485 / 100μlE20-74500-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.