Product Information
Molecular Weight46885 DaObserved Band:48 KD
Protein NameSynaptotagmin-13
Human Gene Id57586
Human Swiss Prot NoQ7L8C5
Mouse Gene Id80976
Mouse Swiss Prot NoQ9EQT6
Rat Gene Id80977
Rat Swiss Prot NoQ925B5
SpecificitySynaptotagmin XIII Polyclonal Antibody detects endogenous levels of Synaptotagmin XIII protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSYT13; KIAA1427; Synaptotagmin-13; Synaptotagmin XIII; SytXIII
Functiondomain:The first C2 domain/C2A does not mediate Ca(2+)-dependent phospholipid binding.,domain:The second C2 domain/C2B domain binds phospholipids regardless of whether calcium is present.,function:May be involved in transport vesicle docking to the plasma membrane.,similarity:Belongs to the synaptotagmin family.,similarity:Contains 2 C2 domains.,subunit:Interacts with NRXN1.,tissue specificity:Expressed in brain, pancreas and kidney.,
Subcellular LocationMembrane ; Single-pass membrane protein .
ExpressionExpressed in brain, pancreas and kidney.
Backgroundsynaptotagmin 13(SYT13) Homo sapiens This gene encodes a member of the large synaptotagmin protein family. Family members have an extracellular N-terminal transmembrane domain and a cytoplasmic C terminus with two tandem C2 domains (C2A and C2B). Synaptotogmin family members can form homo- and heteromeric complexes with each other. They also have different biochemical properties and developmental profiles, and patterns of tissue distribution. Synaptotagmins function as membrane traffickers in multicellular organisms. Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011],