Product Information
Molecular Weight104821 DaObserved Band:105 KD
Protein NameSplicing factor suppressor of white-apricot homolog
Human Gene Id6433
Human Swiss Prot NoQ12872
Mouse Swiss Prot NoQ3USH5
SpecificitySWAP Polyclonal Antibody detects endogenous levels of SWAP protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSFSWAP; SFRS8; SWAP; Splicing factor; suppressor of white-apricot homolog; Splicing factor, arginine/serine-rich 8; Suppressor of white apricot protein homolog
Functionfunction:May function as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 2 SURP motif repeats.,
Subcellular LocationNucleus .
ExpressionBrain,Epithelium,Eye,Placenta,Skin,
Backgroundsplicing factor SWAP homolog(SFSWAP) Homo sapiens This gene encodes a human homolog of Drosophila splicing regulatory protein. This gene autoregulates its expression by control of splicing of its first two introns. In addition, it also regulates the splicing of fibronectin and CD45 genes. Two transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012],