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Cell Signal Transduction Research Antibodies
SURF-1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight33331 DaObserved Band:30 KD
Protein NameSurfeit locus protein 1
Human Gene Id6834
Human Swiss Prot NoQ15526
Mouse Gene Id20930
Mouse Swiss Prot NoP09925
Rat Gene Id64463
Rat Swiss Prot NoQ9QXU2
SpecificitySURF-1 Polyclonal Antibody detects endogenous levels of SURF-1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSURF1; SURF-1; Surfeit locus protein 1
Functiondisease:Defects in SURF1 are a cause of Leigh syndrome (LS) [MIM:256000]. LS is a severe neurological disorder characterized by bilaterally symmetrical necrotic lesions in subcortical brain regions that is commonly associated with systemic cytochrome c oxidase (COX) deficiency.,function:Probably involved in the biogenesis of the COX complex.,similarity:Belongs to the SURF1 family.,
Subcellular LocationMitochondrion inner membrane ; Multi-pass membrane protein .
ExpressionColon,Kidney,Skin,Stomach,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human SURF1. AA range:171-220
Gene NameSURF1
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
BackgroundSURF1, cytochrome c oxidase assembly factor(SURF1) Homo sapiens This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-74471-Conjugate. Price: $485 / Size: 100μl.
E20-74471-FITC$485 / 100μlE20-74471-Biotin$485 / 100μlE20-74471-HRP$485 / 100μlE20-74471-AP$485 / 100μlE20-74471-AF350$485 / 100μlE20-74471-AF405M$485 / 100μlE20-74471-AF488$485 / 100μlE20-74471-AF514$485 / 100μlE20-74471-AF532$485 / 100μlE20-74471-AF555$485 / 100μlE20-74471-AF568$485 / 100μlE20-74471-AF405S$485 / 100μlE20-74471-AF405L$485 / 100μlE20-74471-AF546$485 / 100μlE20-74471-AF594$485 / 100μlE20-74471-AF610$485 / 100μlE20-74471-AF635$485 / 100μlE20-74471-AF647$485 / 100μlE20-74471-AF680$485 / 100μlE20-74471-AF700$485 / 100μlE20-74471-AF750$485 / 100μlE20-74471-AF790$485 / 100μlE20-74471-APC$485 / 100μlE20-74471-PE$485 / 100μlE20-74471-Cy3$485 / 100μlE20-74471-Cy5$485 / 100μlE20-74471-Cy5.5$485 / 100μlE20-74471-Cy7$485 / 100μlE20-74471-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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