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Cell Signal Transduction Research Antibodies

Stonin-1 Polyclonal Antibody

E20-74463Cite ID: EN0054596DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight83141Da
Protein NameStonin-1
Human Gene Id11037
Human Swiss Prot NoQ9Y6Q2
Mouse Swiss Prot NoQ8CDJ8
SpecificityStonin-1 Polyclonal Antibody detects endogenous levels of Stonin-1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSTON1; SALF; SBLF; STN1; Stonin-1; Stoned B-like factor
Observed Band(KD)83
Functioncaution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,function:May be involved in the endocytic machinery.,function:May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription.,miscellaneous:In contrast to other members of the family, it does not contain NPF (Asn-Pro-Phe) sites and thereby does not interact with EPS15, EPS15R and ITSN1.,sequence caution:Chimeric cDNA. The biological existence and relevance of this product of both SALF (AC Q9Y6Q2) and GTF2A1LF genes, creating a chimeric protein of 1182 residues is uncertain.,sequence caution:Chimeric cDNA. The biological existence and relevance of this product of both SALF and GTF2A1LF (AC Q9UNN4) genes, which codes for a chimeric protein of 1
Subcellular Locationcytoplasm,membrane,
ExpressionBrain,Heart,PCR rescued clones,Placenta,Testis,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human STON1. AA range:686-735
Gene NameSTON1
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundstonin 1(STON1) Homo sapiens Endocytosis of cell surface proteins is mediated by a complex molecular machinery that assembles on the inner surface of the plasma membrane. This gene encodes one of two human homologs of the Drosophila melanogaster stoned B protein. This protein is related to components of the endocytic machinery and exhibits a modular structure consisting of an N-terminal proline-rich domain, a central region of homology specific to the human stoned B-like proteins, and a C-terminal region homologous to the mu subunits of adaptor protein (AP) complexes. Read-through transcription of this gene into the neighboring downstream gene, which encodes TFIIA-alpha/beta-like factor, generates a transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010],

Conjugated Antibody

This product is also available conjugated. Format: E20-74463-Conjugate. Price: $485 / Size: 100μl.

E20-74463-FITC$485 / 100μlE20-74463-Biotin$485 / 100μlE20-74463-HRP$485 / 100μlE20-74463-AP$485 / 100μlE20-74463-AF350$485 / 100μlE20-74463-AF405M$485 / 100μlE20-74463-AF488$485 / 100μlE20-74463-AF514$485 / 100μlE20-74463-AF532$485 / 100μlE20-74463-AF555$485 / 100μlE20-74463-AF568$485 / 100μlE20-74463-AF405S$485 / 100μlE20-74463-AF405L$485 / 100μlE20-74463-AF546$485 / 100μlE20-74463-AF594$485 / 100μlE20-74463-AF610$485 / 100μlE20-74463-AF635$485 / 100μlE20-74463-AF647$485 / 100μlE20-74463-AF680$485 / 100μlE20-74463-AF700$485 / 100μlE20-74463-AF750$485 / 100μlE20-74463-AF790$485 / 100μlE20-74463-APC$485 / 100μlE20-74463-PE$485 / 100μlE20-74463-Cy3$485 / 100μlE20-74463-Cy5$485 / 100μlE20-74463-Cy5.5$485 / 100μlE20-74463-Cy7$485 / 100μlE20-74463-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.