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Cell Signal Transduction Research Antibodies

StIp1 Polyclonal Antibody

E20-74459Cite ID: EN0054592DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight92500 DaObserved Band:93 KD
Protein NameElongator complex protein 2
Human Gene Id55250
Human Swiss Prot NoQ6IA86
Mouse Swiss Prot NoQ91WG4
SpecificityStIp1 Polyclonal Antibody detects endogenous levels of StIp1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameELP2; STATIP1; Elongator complex protein 2; ELP2; SHINC-2; STAT3-interacting protein 1; StIP1
Functionfunction:Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.,function:Regulates the ligand-dependent activation of STAT3.,similarity:Belongs to the WD repeat ELP2 family.,similarity:Contains 14 WD repeats.,subunit:Component of the RNA polymerase II elongator complex (Elongator), which consists of IKBKAP/ELP1, STIP1/ELP2, ELP3, ELP4, and two yet unidentified proteins, p30 and p38. Elongator associates with the C-terminal domain (CTD) of Pol II largest subunit. Interacts with STAT3 and JAKs.,
Subcellular LocationCytoplasm . Nucleus .
ExpressionHematopoietic,Liver,Ovary,Uterus,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human ELP2. AA range:771-820
Gene NameELP2
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundelongator acetyltransferase complex subunit 2(ELP2) Homo sapiens The protein encoded by this gene is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin. [provided by RefSeq, May 2016],

Conjugated Antibody

This product is also available conjugated. Format: E20-74459-Conjugate. Price: $485 / Size: 100μl.

E20-74459-FITC$485 / 100μlE20-74459-Biotin$485 / 100μlE20-74459-HRP$485 / 100μlE20-74459-AP$485 / 100μlE20-74459-AF350$485 / 100μlE20-74459-AF405M$485 / 100μlE20-74459-AF488$485 / 100μlE20-74459-AF514$485 / 100μlE20-74459-AF532$485 / 100μlE20-74459-AF555$485 / 100μlE20-74459-AF568$485 / 100μlE20-74459-AF405S$485 / 100μlE20-74459-AF405L$485 / 100μlE20-74459-AF546$485 / 100μlE20-74459-AF594$485 / 100μlE20-74459-AF610$485 / 100μlE20-74459-AF635$485 / 100μlE20-74459-AF647$485 / 100μlE20-74459-AF680$485 / 100μlE20-74459-AF700$485 / 100μlE20-74459-AF750$485 / 100μlE20-74459-AF790$485 / 100μlE20-74459-APC$485 / 100μlE20-74459-PE$485 / 100μlE20-74459-Cy3$485 / 100μlE20-74459-Cy5$485 / 100μlE20-74459-Cy5.5$485 / 100μlE20-74459-Cy7$485 / 100μlE20-74459-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

StIp1 Polyclonal Antibody | EnoGene Biotech Co. Ltd