Product Information
Molecular Weight39851 DaObserved Band:36 KD
Protein NameMetalloreductase STEAP1
Human Gene Id26872
Human Swiss Prot NoQ9UHE8
Mouse Swiss Prot NoQ9CWR7
SpecificitySTEAP1 Polyclonal Antibody detects endogenous levels of STEAP1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSTEAP1; PRSS24; STEAP; Metalloreductase STEAP1; Six-transmembrane epithelial antigen of prostate 1
Functioncofactor:FAD.,function:Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor.,similarity:Belongs to the STEAP family.,similarity:Contains 1 ferric oxidoreductase domain.,tissue specificity:Ubiquitously expressed. Highly expressed in prostate tumors.,
Subcellular LocationEndosome membrane ; Multi-pass membrane protein .
ExpressionUbiquitously expressed. Highly expressed in prostate tumors.
BackgroundSTEAP family member 1(STEAP1) Homo sapiens This gene is predominantly expressed in prostate tissue, and is found to be upregulated in multiple cancer cell lines. The gene product is predicted to be a six-transmembrane protein, and was shown to be a cell surface antigen significantly expressed at cell-cell junctions. [provided by RefSeq, Jul 2008],