STAG3 Polyclonal Antibody

Name: STAG3 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-74434
Price: 225 USD
Availability: InStock

E20-74434Cite ID: EN0054567Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight139034Da

Protein NameCohesin subunit SA-3

Human Gene Id10734

Human Swiss Prot NoQ9UJ98

Mouse Swiss Prot NoO70576

SpecificitySTAG3 Polyclonal Antibody detects endogenous levels of STAG3 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameSTAG3; Cohesin subunit SA-3; SCC3 homolog 3; Stromal antigen 3; Stromalin-3

Observed Band(KD)139

Functionfunction:Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I.,similarity:Belongs to the SCC3 family.,similarity:Contains 1 SCD (stromalin conservative) domain.,subcellular location:Associates with chromatin. In prophase I stage of meiosis, it is found along the axial elements of synaptonemal complexes. In late-pachytene-diplotene, the bulk of protein dissociates from the chromosome arms probably because of phosphorylation by PLK, except at centrom

Subcellular Locationchromosome, centromeric region,synaptonemal complex,lateral element,transverse filament,male germ cell nucleus,extracellular space,nucleus,meiotic cohesin complex,nuclear meiotic cohesin complex,

ExpressionTestis,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human STAG3. AA range:1161-1210

Gene NameSTAG3

DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Backgroundstromal antigen 3(STAG3) Homo sapiens The protein encoded by this gene is expressed in the nucleus and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. A mutation in this gene is associated with premature ovarian failure. Alternate splicing results in multiple transcript variants encoding distinct isoforms. This gene has multiple pseudogenes. [provided by RefSeq, Apr 2014],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-74434-Conjugate. Price: $485 / Size: 100μl.

E20-74434-FITC$485 / 100μlE20-74434-Biotin$485 / 100μlE20-74434-HRP$485 / 100μlE20-74434-AP$485 / 100μlE20-74434-AF350$485 / 100μlE20-74434-AF405M$485 / 100μlE20-74434-AF488$485 / 100μlE20-74434-AF514$485 / 100μlE20-74434-AF532$485 / 100μlE20-74434-AF555$485 / 100μlE20-74434-AF568$485 / 100μlE20-74434-AF405S$485 / 100μlE20-74434-AF405L$485 / 100μlE20-74434-AF546$485 / 100μlE20-74434-AF594$485 / 100μlE20-74434-AF610$485 / 100μlE20-74434-AF635$485 / 100μlE20-74434-AF647$485 / 100μlE20-74434-AF680$485 / 100μlE20-74434-AF700$485 / 100μlE20-74434-AF750$485 / 100μlE20-74434-AF790$485 / 100μlE20-74434-APC$485 / 100μlE20-74434-PE$485 / 100μlE20-74434-Cy3$485 / 100μlE20-74434-Cy5$485 / 100μlE20-74434-Cy5.5$485 / 100μlE20-74434-Cy7$485 / 100μlE20-74434-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.