Product Information
Protein NameSingle-stranded DNA-binding protein mitochondrial
Human Gene Id6742
Human Swiss Prot NoQ04837
Mouse Gene Id381760
Mouse Swiss Prot NoQ9CYR0
Rat Gene Id54304
Rat Swiss Prot NoP28042
SpecificitySSBP1 Polyclonal Antibody detects endogenous levels of SSBP1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSSBP1; SSBP; Single-stranded DNA-binding protein; mitochondrial; Mt-SSB; MtSSB; PWP1-interacting protein 17
Observed Band(KD)17
Functionfunction:This protein binds preferentially and cooperatively to ss-DNA. Probably involved in mitochondrial DNA replication.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 SSB domain.,subunit:Homotetramer.,
Subcellular LocationMitochondrion . Mitochondrion matrix, mitochondrion nucleoid .
ExpressionExpressed in retinal ganglion cells, photoreceptors, pigmented epithelium and fibroblasts (at protein level).
BackgroundSSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010],