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Cell Signal Transduction Research Antibodies
SRp20 Polyclonal Antibody
Human;Mouse;Rat
WB;IHC-p;IF(paraffin section);ELISA
Polyclonal, Rabbit,IgG
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human SRF. AA range:71-120
Gene NameSRF
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Product Information
Protein NameSerum response factor
Human Gene Id6722
Human Swiss Prot NoP11831
Mouse Gene Id20807
Mouse Swiss Prot NoQ9JM73
SpecificitySRF Polyclonal Antibody detects endogenous levels of SRF protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSRF; Serum response factor; SRF
Observed Band(KD)67
Functionfunction:SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Required for cardiac differentation and maturation.,PTM:Phosphorylated by PRKDC.,similarity:Contains 1 MADS-box domain.,subunit:Binds DNA as a multimer, probably a dimer. Interacts with MLLT7/FOXO4, NKX3A and SSRP1. Interacts with ARID2 and SRFBP1 (By similarity). Forms complexes with ARID2, MYOCD, NKX2-5 and SRFBP1.,
Subcellular LocationNucleus .
ExpressionBrain,Epithelium,Lung,Lymph,
BackgroundThis gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014],
Conjugated Antibody
This product is also available conjugated. Format: E20-74417-Conjugate. Price: $485 / Size: 100μl.
E20-74417-FITC$485 / 100μlE20-74417-Biotin$485 / 100μlE20-74417-HRP$485 / 100μlE20-74417-AP$485 / 100μlE20-74417-AF350$485 / 100μlE20-74417-AF405M$485 / 100μlE20-74417-AF488$485 / 100μlE20-74417-AF514$485 / 100μlE20-74417-AF532$485 / 100μlE20-74417-AF555$485 / 100μlE20-74417-AF568$485 / 100μlE20-74417-AF405S$485 / 100μlE20-74417-AF405L$485 / 100μlE20-74417-AF546$485 / 100μlE20-74417-AF594$485 / 100μlE20-74417-AF610$485 / 100μlE20-74417-AF635$485 / 100μlE20-74417-AF647$485 / 100μlE20-74417-AF680$485 / 100μlE20-74417-AF700$485 / 100μlE20-74417-AF750$485 / 100μlE20-74417-AF790$485 / 100μlE20-74417-APC$485 / 100μlE20-74417-PE$485 / 100μlE20-74417-Cy3$485 / 100μlE20-74417-Cy5$485 / 100μlE20-74417-Cy5.5$485 / 100μlE20-74417-Cy7$485 / 100μlE20-74417-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
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- Transfection Reagent
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