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SR-5A Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-74405

  • Amount:

    100ul

  • Molecular Weight:

    40255Da

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human HTR5A. AA range:15-64

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    HTR5A

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

  • Background:

    5-hydroxytryptamine receptor 5A(HTR5A) Homo sapiens The neurotransmitter serotonin (5-hydroxytryptamine, 5-HT) has been implicated in a wide range of psychiatric conditions and also has vasoconstrictive and vasodilatory effects. The gene described in this record is a member of 5-hydroxytryptamine (serotonin) receptor family and encodes a multi-pass membrane protein that functions as a receptor for 5-hydroxytryptamine and couples to G-proteins. This protein has been shown to function in part through the regulation of intracellular Ca2+ mobilization. [provided by RefSeq, Jul 2008],

  • Protein Name:

    5-hydroxytryptamine receptor 5A

  • Human Gene Id:

    3361

  • Human Swiss Prot No:

    P47898

  • Mouse Swiss Prot No:

    P30966

  • Specificity:

    SR-5A Polyclonal Antibody detects endogenous levels of SR-5A protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    HTR5A; 5-hydroxytryptamine receptor 5A; 5-HT-5; 5-HT-5A; 5-HT5A; Serotonin receptor 5A

  • Observed Band(KD):

    36

  • Function:

    function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins.,similarity:Belongs to the G-protein coupled receptor 1 family.,

  • Subcellular Location:

    Cell membrane; Multi-pass membrane protein.

  • Expression:

    Brain,Cerebellum,

  • Immunofluorescence analysis of LOVO cells, using HTR5A Antibody. The picture on the right is blocked with the synthesized peptide.

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