SR-4 Polyclonal Antibody

Name: SR-4 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-74403
Price: 225 USD
Availability: InStock

E20-74403Cite ID: EN0054536Datasheet COA MSDS

ReactivityHuman;Mouse;Rat

ApplicationsWB;IHC-p;IF/ICC;ELISA

SourcePolyclonal, Rabbit,IgG

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human 5-HT-4. AA range:21-70

Gene NameHTR4

DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Product Information

Protein Name5-hydroxytryptamine receptor 4

Human Gene Id3360

Human Swiss Prot NoQ13639

Mouse Gene Id15562

Mouse Swiss Prot NoP97288

Rat Gene Id25324

Rat Swiss Prot NoQ62758

SpecificitySR-4 Polyclonal Antibody detects endogenous levels of SR-4 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameHTR4; 5-hydroxytryptamine receptor 4; 5-HT-4; 5-HT4; Serotonin receptor 4

Observed Band(KD)43

Functionalternative products:Additional isoforms seem to exist,function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.,similarity:Belongs to the G-protein coupled receptor 1 family.,subcellular location:Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli.,subunit:Isoform 5-HT4(A) interacts with MAGI2, MPP3, SLC9A3R1 and SNX27 isoforms 1 and 2. Isoform 5-HT4(E) interacts with INADL, NOS1 and SEC23A. Isoform 5-HT4(A) forms a complex including SLC9A3R1 and EZR.,tissue specificity:Isoform 5-HT4(A) is expressed in ileum, brain, and atrium, but not in the ventricle.

Subcellular LocationCell membrane; Multi-pass membrane protein. Endosome. Interaction with SNX27 mediates recruitment to early endosomes, while interaction with SLC9A3R1 and EZR might target the protein to specialized subcellular regions, such as microvilli. .

ExpressionIsoform 5-HT4(A) is expressed in ileum, brain, and atrium, but not in the ventricle.

BackgroundThis gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-74403-Conjugate. Price: $485 / Size: 100μl.

E20-74403-FITC$485 / 100μlE20-74403-Biotin$485 / 100μlE20-74403-HRP$485 / 100μlE20-74403-AP$485 / 100μlE20-74403-AF350$485 / 100μlE20-74403-AF405M$485 / 100μlE20-74403-AF488$485 / 100μlE20-74403-AF514$485 / 100μlE20-74403-AF532$485 / 100μlE20-74403-AF555$485 / 100μlE20-74403-AF568$485 / 100μlE20-74403-AF405S$485 / 100μlE20-74403-AF405L$485 / 100μlE20-74403-AF546$485 / 100μlE20-74403-AF594$485 / 100μlE20-74403-AF610$485 / 100μlE20-74403-AF635$485 / 100μlE20-74403-AF647$485 / 100μlE20-74403-AF680$485 / 100μlE20-74403-AF700$485 / 100μlE20-74403-AF750$485 / 100μlE20-74403-AF790$485 / 100μlE20-74403-APC$485 / 100μlE20-74403-PE$485 / 100μlE20-74403-Cy3$485 / 100μlE20-74403-Cy5$485 / 100μlE20-74403-Cy5.5$485 / 100μlE20-74403-Cy7$485 / 100μlE20-74403-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.