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SR-3D Polyclonal Antibody
Datasheet
Catalog Number:
E20-74402Amount:
100ulMolecular Weight:
50191(DA) Observed Band(KD)50Price:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
Synthesized peptide derived from SR-3D . at AA range: 10-90Source:
Polyclonal, Rabbit
- Western Blot analysis of HT-29 cells using SR-3D Polyclonal Antibody
Gene Name:
HTR3DDilution:
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.Protein Name:
5-hydroxytryptamine receptor 3DHuman Gene Id:
200909Human Swiss Prot No:
Q70Z44Specificity:
SR-3D Polyclonal Antibody detects endogenous levels of SR-3D protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
HTR3D; 5-hydroxytryptamine receptor 3D; 5-HT3-D; 5-HT3D; Serotonin receptor 3DBackground:
5-hydroxytryptamine receptor 3D(HTR3D) Homo sapiens The protein encoded this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit D of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a mitogen and a hormone. This hormone has been linked to neuropsychiatric disorders, including anxiety, depression, and migraine. Serotonin receptors causes fast and depolarizing responses in neurons following activation. The genes encoding subunits C, D and E of this type 3 receptor form a cluster on chromosome 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009],Function:
function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel.,similarity:Belongs to the ligand-gated ionic channel (TC 1.A.9) family.,subcellular location:Presumably retained within the endoplasmic reticulum unless complexed with HTR3A.,subunit:Forms a pentaheteromeric complex with HTR3A, homomeric complex being not functional.,tissue specificity:Expressed in liver, as well as fetal and adult colon and kidney.,Subcellular Location:
plasma membrane,acetylcholine-gated channel complex,integral component of membrane,
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Catalog Number
- Amount:100ul
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