SR-2B Polyclonal Antibody

Name: SR-2B Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-74398
Price: 225 USD
Availability: InStock

E20-74398Cite ID: EN0054531Datasheet COA MSDS

ReactivityHuman;Rat;Mouse;

ApplicationsWB;IF/ICC;ELISA

SourcePolyclonal, Rabbit,IgG

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human HTR2B. AA range:15-64

Gene NameHTR2B

DilutionWestern Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Product Information

Protein Name5-hydroxytryptamine receptor 2B

Human Gene Id3357

Human Swiss Prot NoP41595

Mouse Swiss Prot NoQ02152

SpecificitySR-2B Polyclonal Antibody detects endogenous levels of SR-2B protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameHTR2B; 5-hydroxytryptamine receptor 2B; 5-HT-2B; 5-HT2B; Serotonin receptor 2B

Observed Band(KD)54kD

Functionfunction:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with MPDZ.,tissue specificity:Detected in most peripheral organs. Only low expression levels were found in the brain.,

Subcellular LocationCell membrane ; Multi-pass membrane protein . Cell junction, synapse, synaptosome .

ExpressionUbiquitous. Detected in liver, kidney, heart, pulmonary artery, and intestine. Detected at lower levels in blood, placenta and brain, especially in cerebellum, occipital cortex and frontal cortex.

BackgroundThis gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-74398-Conjugate. Price: $485 / Size: 100μl.

E20-74398-FITC$485 / 100μlE20-74398-Biotin$485 / 100μlE20-74398-HRP$485 / 100μlE20-74398-AP$485 / 100μlE20-74398-AF350$485 / 100μlE20-74398-AF405M$485 / 100μlE20-74398-AF488$485 / 100μlE20-74398-AF514$485 / 100μlE20-74398-AF532$485 / 100μlE20-74398-AF555$485 / 100μlE20-74398-AF568$485 / 100μlE20-74398-AF405S$485 / 100μlE20-74398-AF405L$485 / 100μlE20-74398-AF546$485 / 100μlE20-74398-AF594$485 / 100μlE20-74398-AF610$485 / 100μlE20-74398-AF635$485 / 100μlE20-74398-AF647$485 / 100μlE20-74398-AF680$485 / 100μlE20-74398-AF700$485 / 100μlE20-74398-AF750$485 / 100μlE20-74398-AF790$485 / 100μlE20-74398-APC$485 / 100μlE20-74398-PE$485 / 100μlE20-74398-Cy3$485 / 100μlE20-74398-Cy5$485 / 100μlE20-74398-Cy5.5$485 / 100μlE20-74398-Cy7$485 / 100μlE20-74398-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.