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SNAT2 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-74354

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human SLC38A2. AA range:151-200

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    SLC38A2

  • Dilution:

    Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

  • Western blot analysis of lysates from HeLa cells, using SLC38A2 Antibody. The lane on the right is blocked with the synthesized peptide.

  • Background:

    enzyme regulation:Inhibited by N-methyl-D-glucamine and probably choline.,function:Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta.,induction:Up-regulated upon hypertonic conditions and amino acid deprivation.,miscellaneous:Depletion of SCL38A2 by siRNA prevents the recovery of cells from hypertonic stress.,PTM:Polyubiquitination by NEDD4L regulates the degradation and the activity of SLC38A2.,similarity:Belongs to the amino acid/polyamine transporter 2 family.,subcellular location:Insulin promotes recruitment to the plasma membrane from a pool localized in the trans-Golgi network or endosomes (By similarity). Enriched in the somatodendritic compartment of neurons, it is also detected at the axonal shaft but excluded from the nerve terminal.,tissue specificity:Ubiquitously expressed. Widely expressed in the central nervous system with higher concentrations in caudal regions. Expressed by glutamatergic and GABAergic neurons together with astrocytes and other non-neuronal cells in the cerebral cortex (at protein level).,

  • Protein Name:

    Sodium-coupled neutral amino acid transporter 2

  • Human Gene Id:

    54407

  • Human Swiss Prot No:

    Q96QD8

  • Mouse Swiss Prot No:

    Q8CFE6

  • Specificity:

    SNAT2 Polyclonal Antibody detects endogenous levels of SNAT2 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    SLC38A2; ATA2; KIAA1382; SAT2; SNAT2; Sodium-coupled neutral amino acid transporter 2; Amino acid transporter A2; Protein 40-9-1; Solute carrier family 38 member 2; System A amino acid transporter 2; System A transporter 1; System N amino a

  • MolecularWeight(Da):

    56026

  • Observed Band(KD):

    50

  • Function:

    enzyme regulation:Inhibited by N-methyl-D-glucamine and probably choline.,function:Functions as a sodium-dependent amino acid transporter. Mediates the saturable, pH-sensitive and electrogenic cotransport of neutral amino acids and sodium ions with a stoichiometry of 1:1. May function in the transport of amino acids at the blood-brain barrier and in the supply of maternal nutrients to the fetus through the placenta.,induction:Up-regulated upon hypertonic conditions and amino acid deprivation.,miscellaneous:Depletion of SCL38A2 by siRNA prevents the recovery of cells from hypertonic stress.,PTM:Polyubiquitination by NEDD4L regulates the degradation and the activity of SLC38A2.,similarity:Belongs to the amino acid/polyamine transporter 2 family.,subcellular location:Insulin promotes recruitment to the plasma membrane from a pool localized in the trans-Golgi network or endosomes (By similar

  • Subcellular Location:

    plasma membrane,integral component of plasma membrane,brush border,integral component of membrane,axon,dendrite,sarcolemma,neuronal cell body,

  • Expression:

    Brain,Epithelium,Eye,Hepatoma,Liver,Lung,Teratocarcinoma,

  • Western blot analysis of the lysates from HeLa cells using SLC38A2 antibody.

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Catalog Number

  • Amount:100ul
  • Price:225$

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SNAT2 Polyclonal Antibody | EnoGene Biotech Co. Ltd