SLU7 Polyclonal Antibody

Name: SLU7 Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-74322
Price: 225 USD
Availability: InStock

E20-74322Cite ID: EN0054455Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight68357

Protein NamePre-mRNA-splicing factor SLU7

Human Gene Id10569

Human Swiss Prot NoO95391

Mouse Gene Id193116

Mouse Swiss Prot NoQ8BHJ9

Rat Gene Id303057

Rat Swiss Prot NoQ80ZG5

SpecificitySLU7 Polyclonal Antibody detects endogenous levels of SLU7 protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameSLU7; Pre-mRNA-splicing factor SLU7; hSlu7

Observed Band(KD)65

Functiondomain:The CCHC-type zinc finger is required to retain the protein within the nucleus and prevent its shuttle back to the cytoplasm via the CRM1 pathway.,function:Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Required for holding exon 1 properly in the spliceosome and for correct AG identification when more than one possible AG exists in 3'-splicing site region. May be involved in the activation of proximal AG. Probably also involved in alternative splicing regulation.,similarity:Belongs to the SLU7 family.,similarity:Contains 1 CCHC-type zinc finger.,subcellular location:Predominantly nuclear. Shuttling between the nucleus and the cytoplasm is regulated by the CCHC-type zinc finger. Upon UV-C stress stimulus, the nuclear concentration of the protein

Subcellular Locationnucleus,nucleoplasm,spliceosomal complex,cytoplasm,membrane,nuclear speck,small nuclear ribonucleoprotein complex,intracellular membrane-bounded organelle,catalytic step 2 spliceosome,

ExpressionColon,Epithelium,Eye,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human SLU7. AA range:113-162

Gene NameSLU7

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

BackgroundSLU7 homolog, splicing factor(SLU7) Homo sapiens Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is a splicing factor that has been found to be essential during the second catalytic step in the pre-mRNA splicing process. It associates with the spliceosome and contains a zinc knuckle motif that is found in other splicing factors and is involved in protein-nucleic acid and protein-protein interactions. [provided by RefSeq, Jul 2008],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-74322-Conjugate. Price: $485 / Size: 100μl.

E20-74322-FITC$485 / 100μlE20-74322-Biotin$485 / 100μlE20-74322-HRP$485 / 100μlE20-74322-AP$485 / 100μlE20-74322-AF350$485 / 100μlE20-74322-AF405M$485 / 100μlE20-74322-AF488$485 / 100μlE20-74322-AF514$485 / 100μlE20-74322-AF532$485 / 100μlE20-74322-AF555$485 / 100μlE20-74322-AF568$485 / 100μlE20-74322-AF405S$485 / 100μlE20-74322-AF405L$485 / 100μlE20-74322-AF546$485 / 100μlE20-74322-AF594$485 / 100μlE20-74322-AF610$485 / 100μlE20-74322-AF635$485 / 100μlE20-74322-AF647$485 / 100μlE20-74322-AF680$485 / 100μlE20-74322-AF700$485 / 100μlE20-74322-AF750$485 / 100μlE20-74322-AF790$485 / 100μlE20-74322-APC$485 / 100μlE20-74322-PE$485 / 100μlE20-74322-Cy3$485 / 100μlE20-74322-Cy5$485 / 100μlE20-74322-Cy5.5$485 / 100μlE20-74322-Cy7$485 / 100μlE20-74322-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.