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Cell Signal Transduction Research Antibodies
SEMA3A Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight88889 Da
Protein NameSemaphorin-3A
Human Gene Id10371
Human Swiss Prot NoQ14563
Mouse Gene Id20346
Mouse Swiss Prot NoO08665
Rat Gene Id29751
Rat Swiss Prot NoQ63548
SpecificitySEMA3A Polyclonal Antibody detects endogenous levels of SEMA3A protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSEMA3A; SEMAD; Semaphorin-3A; Semaphorin III; Sema III
Functiondomain:Strong binding to neuropilin is mediated by the carboxy third of the protein.,function:Induces the collapse and paralysis of neuronal growth cones. Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain.,
Subcellular Locationextracellular region,extracellular space,axon,dendrite,
ExpressionFetal brain,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human SEMA3A. AA range:688-737
Gene NameSEMA3A
DilutionWB 1:500-2000 ,Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Backgroundsemaphorin 3A(SEMA3A) Homo sapiens This gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines. Also, aberrant release of this protein is associated with the progression of Alzheimer's disease. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-74232-Conjugate. Price: $485 / Size: 100μl.
E20-74232-FITC$485 / 100μlE20-74232-Biotin$485 / 100μlE20-74232-HRP$485 / 100μlE20-74232-AP$485 / 100μlE20-74232-AF350$485 / 100μlE20-74232-AF405M$485 / 100μlE20-74232-AF488$485 / 100μlE20-74232-AF514$485 / 100μlE20-74232-AF532$485 / 100μlE20-74232-AF555$485 / 100μlE20-74232-AF568$485 / 100μlE20-74232-AF405S$485 / 100μlE20-74232-AF405L$485 / 100μlE20-74232-AF546$485 / 100μlE20-74232-AF594$485 / 100μlE20-74232-AF610$485 / 100μlE20-74232-AF635$485 / 100μlE20-74232-AF647$485 / 100μlE20-74232-AF680$485 / 100μlE20-74232-AF700$485 / 100μlE20-74232-AF750$485 / 100μlE20-74232-AF790$485 / 100μlE20-74232-APC$485 / 100μlE20-74232-PE$485 / 100μlE20-74232-Cy3$485 / 100μlE20-74232-Cy5$485 / 100μlE20-74232-Cy5.5$485 / 100μlE20-74232-Cy7$485 / 100μlE20-74232-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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