Product Information
Molecular Weight86479 Da
Protein NameProtein transport protein Sec23B
Human Gene Id10483
Human Swiss Prot NoQ15437
Mouse Gene Id27054
Mouse Swiss Prot NoQ9D662
SpecificitySec23B Polyclonal Antibody detects endogenous levels of Sec23B protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameSEC23B; Protein transport protein Sec23B; SEC23-related protein B
Observed Band(KD)86
Functionfunction:Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.,similarity:Belongs to the SEC23/SEC24 family. SEC23 subfamily.,subunit:COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1.,
Subcellular LocationGolgi membrane,endoplasmic reticulum,endoplasmic reticulum membrane,Golgi apparatus,endomembrane system,membrane,COPII vesicle coat,endoplasmic reticulum-Golgi intermediate compartment membrane,intracellular membrane-bounded organelle,GO
ExpressionB-cell,Cervix,Placenta,Uterus,
BackgroundSec23 homolog B, coat complex II component(SEC23B) Homo sapiens The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010],