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Rho H Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-74083
  • Amount:

    100ul
  • Price:

    225$
  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human RhoH. AA range:141-190
  • Source:

    Polyclonal, Rabbit
  • Gene Name:

    RhoH
  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
  • Immunofluorescence analysis of A549 cells, using RhoH Antibody. The picture on the right is blocked with the synthesized peptide.
  • Background:

    ras homolog family member H(RHOH) Homo sapiens The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2013],
  • Protein Name:

    Rho-related GTP-binding protein RhoH
  • Human Gene Id:

    399
  • Human Swiss Prot No:

    Q15669
  • Mouse Gene Id:

    74734
  • Mouse Swiss Prot No:

    Q9D3G9
  • Specificity:

    Rho H Polyclonal Antibody detects endogenous levels of Rho H protein.
  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Concentration:

    1 mg/ml
  • Storage Stability:

    -20°C/1 year
  • Other Name:

    RHOH; ARHH; TTF; Rho-related GTP-binding protein RhoH; GTP-binding protein TTF; Translocation three four protein
  • MolecularWeight(Da):

    21331
  • Observed Band(KD):

    21
  • Function:

    disease:A chromosomal aberration involving RHOH is found in a non-Hodgkin lymphoma cell line. Translocation t(3;4)(q27;p11) with BCL6.,similarity:Belongs to the small GTPase superfamily. Rho family.,tissue specificity:Transcribed only in hemopoietic cells.,
  • Subcellular Location:

    immunological synapse,intracellular,cytoplasm,cytosol,plasma membrane,
  • Expression:

    B-cell,
  • Western blot analysis of lysates from HT-29 cells, using RhoH Antibody. The lane on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

Add to Cart

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