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Cell Signal Transduction Research Antibodies
RGS14 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight64922Da
Protein NameRegulator of G-protein signaling 14
Human Gene Id10636
Human Swiss Prot NoO43566
Mouse Gene Id51791
Mouse Swiss Prot NoP97492
Rat Gene Id114705
Rat Swiss Prot NoO08773
SpecificityRGS14 Polyclonal Antibody detects endogenous levels of RGS14 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameRGS14; Regulator of G-protein signaling 14; RGS14
Observed Band(KD)65
Functionfunction:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form.,similarity:Contains 1 GoLoco domain.,similarity:Contains 1 RGS domain.,similarity:Contains 2 RBD (Ras-binding) domains.,
Subcellular Locationspindle pole,intracellular,nucleus,cytoplasm,centrosome,spindle,microtubule,plasma membrane,postsynaptic density,nuclear body,PML body,cell junction,dendrite,dendritic spine,posts
ExpressionBrain,Caudate nucleus,Colon,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human RGS14. AA range:125-174
Gene NameRGS14
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundregulator of G-protein signaling 14(RGS14) Homo sapiens This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-74073-Conjugate. Price: $485 / Size: 100μl.
E20-74073-FITC$485 / 100μlE20-74073-Biotin$485 / 100μlE20-74073-HRP$485 / 100μlE20-74073-AP$485 / 100μlE20-74073-AF350$485 / 100μlE20-74073-AF405M$485 / 100μlE20-74073-AF488$485 / 100μlE20-74073-AF514$485 / 100μlE20-74073-AF532$485 / 100μlE20-74073-AF555$485 / 100μlE20-74073-AF568$485 / 100μlE20-74073-AF405S$485 / 100μlE20-74073-AF405L$485 / 100μlE20-74073-AF546$485 / 100μlE20-74073-AF594$485 / 100μlE20-74073-AF610$485 / 100μlE20-74073-AF635$485 / 100μlE20-74073-AF647$485 / 100μlE20-74073-AF680$485 / 100μlE20-74073-AF700$485 / 100μlE20-74073-AF750$485 / 100μlE20-74073-AF790$485 / 100μlE20-74073-APC$485 / 100μlE20-74073-PE$485 / 100μlE20-74073-Cy3$485 / 100μlE20-74073-Cy5$485 / 100μlE20-74073-Cy5.5$485 / 100μlE20-74073-Cy7$485 / 100μlE20-74073-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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