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Cell Signal Transduction Research Antibodies

Relaxin Receptor 2 Polyclonal AntibodyAntibody

E20-74042Cite ID: EN0054175DatasheetCOAMSDS
Polyclonal, Rabbit
$225/ 100ul
Quantity
Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

Product Information

Molecular Weight86453Da
Protein NameRelaxin receptor 2
Human Gene Id122042
Human Swiss Prot NoQ8WXD0
Mouse Gene Id140498
Mouse Swiss Prot NoQ91ZZ5
SpecificityRelaxin Receptor 2 Polyclonal Antibody detects endogenous levels of Relaxin Receptor 2 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameRXFP2; GPR106; GREAT; LGR8; Relaxin receptor 2; G-protein coupled receptor 106; G-protein coupled receptor affecting testicular descent; Leucine-rich repeat-containing G-protein coupled receptor 8; Relaxin family peptide receptor 2
Observed Band(KD)86
Functioncaution:It is uncertain whether Met-1 or Met-18 is the initiator.,disease:Defects in RXFP2 are a cause of cryptorchidism [MIM:219050]; also known as impaired testicular descent. It is one of the most frequent congenital abnormalities in humans, involving 2-5% of male births. Cryptorchidism is associated with increased risk of infertility and testicular cancer.,function:Receptor for relaxin. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. May also be a receptor for Leydig insulin-like peptide (INSL3).,similarity:Belongs to the G-protein coupled receptor 1 family.,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 10 LRR (leucine-rich) repeats.,tissue specificity:Expressed mainly in the brain, kidney, muscle, testis, thyroid, uterus, peripheral blood cells and bone marrow.,
Subcellular Locationplasma membrane,integral component of membrane,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human RXFP2. AA range:113-162
Gene NameRXFP2
DilutionWestern Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundrelaxin/insulin like family peptide receptor 2(RXFP2) Homo sapiens This gene encodes a member of the GPCR (G protein-coupled, 7-transmembrane receptor) family. Mutations in this gene are associated with cryptorchidism. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009],

Conjugated Antibody

This product is also available conjugated. Format: E20-74042-Conjugate. Price: $485 / Size: 100μl.

E20-74042-FITC$485 / 100μlE20-74042-Biotin$485 / 100μlE20-74042-HRP$485 / 100μlE20-74042-AP$485 / 100μlE20-74042-AF350$485 / 100μlE20-74042-AF405M$485 / 100μlE20-74042-AF488$485 / 100μlE20-74042-AF514$485 / 100μlE20-74042-AF532$485 / 100μlE20-74042-AF555$485 / 100μlE20-74042-AF568$485 / 100μlE20-74042-AF405S$485 / 100μlE20-74042-AF405L$485 / 100μlE20-74042-AF546$485 / 100μlE20-74042-AF594$485 / 100μlE20-74042-AF610$485 / 100μlE20-74042-AF635$485 / 100μlE20-74042-AF647$485 / 100μlE20-74042-AF680$485 / 100μlE20-74042-AF700$485 / 100μlE20-74042-AF750$485 / 100μlE20-74042-AF790$485 / 100μlE20-74042-APC$485 / 100μlE20-74042-PE$485 / 100μlE20-74042-Cy3$485 / 100μlE20-74042-Cy5$485 / 100μlE20-74042-Cy5.5$485 / 100μlE20-74042-Cy7$485 / 100μlE20-74042-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.

Relaxin Receptor 2 Polyclonal AntibodyAntibody | EnoGene Biotech Co. Ltd