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Cell Signal Transduction Research Antibodies
R-cadherin Polyclonal Antibody
Human;Mouse
IHC-p;IF/ICC;ELISA
Polyclonal, Rabbit,IgG
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight100281Da
Protein NameCadherin-4
Human Gene Id1002
Human Swiss Prot NoP55283
Mouse Gene Id12561
Mouse Swiss Prot NoP39038
SpecificityR-cadherin Polyclonal Antibody detects endogenous levels of R-cadherin protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameCDH4; Cadherin-4; Retinal cadherin; R-CAD; R-cadherin
Functionfunction:Cadherins are calcium dependent cell adhesion proteins.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May play an important role in retinal development.,similarity:Contains 5 cadherin domains.,tissue specificity:Expressed mainly in brain but also found in other tissues.,
Subcellular LocationCell membrane; Single-pass type I membrane protein.
ExpressionExpressed mainly in brain but also found in other tissues.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human CDH4. AA range:731-780
Gene NameCDH4
DilutionImmunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
BackgroundThis gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011],
Conjugated Antibody
This product is also available conjugated. Format: E20-74030-Conjugate. Price: $485 / Size: 100μl.
E20-74030-FITC$485 / 100μlE20-74030-Biotin$485 / 100μlE20-74030-HRP$485 / 100μlE20-74030-AP$485 / 100μlE20-74030-AF350$485 / 100μlE20-74030-AF405M$485 / 100μlE20-74030-AF488$485 / 100μlE20-74030-AF514$485 / 100μlE20-74030-AF532$485 / 100μlE20-74030-AF555$485 / 100μlE20-74030-AF568$485 / 100μlE20-74030-AF405S$485 / 100μlE20-74030-AF405L$485 / 100μlE20-74030-AF546$485 / 100μlE20-74030-AF594$485 / 100μlE20-74030-AF610$485 / 100μlE20-74030-AF635$485 / 100μlE20-74030-AF647$485 / 100μlE20-74030-AF680$485 / 100μlE20-74030-AF700$485 / 100μlE20-74030-AF750$485 / 100μlE20-74030-AF790$485 / 100μlE20-74030-APC$485 / 100μlE20-74030-PE$485 / 100μlE20-74030-Cy3$485 / 100μlE20-74030-Cy5$485 / 100μlE20-74030-Cy5.5$485 / 100μlE20-74030-Cy7$485 / 100μlE20-74030-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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