Product Information
Molecular Weight30956Da
Protein NameRas-related protein Rab-40B
Human Gene Id10966
Human Swiss Prot NoQ12829
Mouse Swiss Prot NoQ8VHP8
SpecificityRab 40B Polyclonal Antibody detects endogenous levels of Rab 40B protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameRAB40B; SEC4L; Ras-related protein Rab-40B; SOCS box-containing protein RAR; Protein Rar
Observed Band(KD)34
Functiondomain:The SOCS box domain mediates the interaction with the Elongin BC complex, an adapter module in different E3 ubiquitin ligase complexes.,function:May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,similarity:Belongs to the small GTPase superfamily. Rab family.,similarity:Contains 1 SOCS box domain.,
Subcellular Locationintracellular,nuclear envelope,plasma membrane,perinuclear region of cytoplasm,
ExpressionBrain,Hippocampus,
BackgroundRAB40B, member RAS oncogene family(RAB40B) Homo sapiens The protein encoded by this gene has similarity to a yeast protein which suggests a role of the gene product in regulating secretory vesicles. [provided by RefSeq, Jul 2008],