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PP2A-B56-δ Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-73829

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human PPP2R5D. AA range:544-593

  • Source:

    Polyclonal, Rabbit

  • Western Blot analysis of 293T cells using PP2A-B56-δ Polyclonal Antibody diluted at 1:1000

  • Gene Name:

    PPP2R5D

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

  • Background:

    protein phosphatase 2 regulatory subunit B'delta(PPP2R5D) Homo sapiens The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

  • Protein Name:

    Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform

  • Human Gene Id:

    5528

  • Human Swiss Prot No:

    Q14738

  • Specificity:

    PP2A-B56-δ Polyclonal Antibody detects endogenous levels of PP2A-B56-δ protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    PPP2R5D; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; PP2A B subunit isoform B'-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A B subunit isoform R5-delta

  • MolecularWeight(Da):

    69992

  • Observed Band(KD):

    70

  • Function:

    function:The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.,induction:By retinoic acid; in neuroblastoma cell lines.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the phosphatase 2A regulatory subunit B56 family.,subcellular location:Nuclear in interphase, nuclear during mitosis.,subunit:PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins,

  • Subcellular Location:

    protein phosphatase type 2A complex,nucleus,nucleoplasm,cytosol,

  • Expression:

    Aorta endothelial cell,Bone marrow,Brain cortex,Col

  • Western blot analysis of lysates from Jurkat and HUVEC cells, using PPP2R5D Antibody. The lane on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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PP2A-B56-δ Polyclonal Antibody | EnoGene Biotech Co. Ltd