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Cell Signal Transduction Research Antibodies
POLR3C Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight60612 Da
Protein NameDNA-directed RNA polymerase III subunit RPC3
Human Gene Id10623
Human Swiss Prot NoQ9BUI4
Mouse Swiss Prot NoQ9D483
SpecificityPOLR3C Polyclonal Antibody detects endogenous levels of POLR3C protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NamePOLR3C; DNA-directed RNA polymerase III subunit RPC3; RNA polymerase III subunit C3; DNA-directed RNA polymerase III subunit C; RNA polymerase III 62 kDa subunit; RPC62
Observed Band(KD)60
Functiondisease:Antibodies against POLR3C were found in the sera of patients with systemic sclerosis (SSc).,function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation.,similarity:Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). RPC3/POLR3C, RPC6/POLR3F and RPC7/POLR3G form a P
Subcellular Locationnucleus,nucleoplasm,DNA-directed RNA polymerase III complex,cytosol,
ExpressionCervix carcinoma,Lung,Ovary,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human RPC3. AA range:191-240
Gene NamePOLR3C
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Backgrounddisease:Antibodies against POLR3C were found in the sera of patients with systemic sclerosis (SSc).,function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation.,similarity:Belongs to the eukaryotic RPC3/POLR3C RNA polymerase subunit family.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits (By similarity). RPC3/POLR3C, RPC6/POLR3F and RPC7/POLR3G form a Pol III subcomplex. Interacts with GTF3C4.,
Conjugated Antibody
This product is also available conjugated. Format: E20-73815-Conjugate. Price: $485 / Size: 100μl.
E20-73815-FITC$485 / 100μlE20-73815-Biotin$485 / 100μlE20-73815-HRP$485 / 100μlE20-73815-AP$485 / 100μlE20-73815-AF350$485 / 100μlE20-73815-AF405M$485 / 100μlE20-73815-AF488$485 / 100μlE20-73815-AF514$485 / 100μlE20-73815-AF532$485 / 100μlE20-73815-AF555$485 / 100μlE20-73815-AF568$485 / 100μlE20-73815-AF405S$485 / 100μlE20-73815-AF405L$485 / 100μlE20-73815-AF546$485 / 100μlE20-73815-AF594$485 / 100μlE20-73815-AF610$485 / 100μlE20-73815-AF635$485 / 100μlE20-73815-AF647$485 / 100μlE20-73815-AF680$485 / 100μlE20-73815-AF700$485 / 100μlE20-73815-AF750$485 / 100μlE20-73815-AF790$485 / 100μlE20-73815-APC$485 / 100μlE20-73815-PE$485 / 100μlE20-73815-Cy3$485 / 100μlE20-73815-Cy5$485 / 100μlE20-73815-Cy5.5$485 / 100μlE20-73815-Cy7$485 / 100μlE20-73815-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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