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PLA1A Polyclonal Antibody
Datasheet
Catalog Number:
E20-73783Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human PLA1A. AA range:381-430Source:
Polyclonal, Rabbit
- Western Blot analysis of 3T3 cells using PLA1A Polyclonal Antibody
Gene Name:
PLA1ADilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.Background:
phospholipase A1 member A(PLA1A) Homo sapiens The protein encoded by this gene is a phospholipase that hydrolyzes fatty acids at the sn-1 position of phosphatidylserine and 1-acyl-2-lysophosphatidylserine. This secreted protein hydrolyzes phosphatidylserine in liposomes. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011],Protein Name:
Phospholipase A1 member AHuman Gene Id:
51365Human Swiss Prot No:
Q53H76Mouse Swiss Prot No:
Q8VI78Specificity:
PLA1A Polyclonal Antibody detects endogenous levels of PLA1A protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
PLA1A; NMD; PSPLA1; Phospholipase A1 member A; Phosphatidylserine-specific phospholipase A1; PS-PLA1MolecularWeight(Da):
49715Observed Band(KD):
50Function:
function:Hydrolyzes the ester bond at the sn-1 position of glycerophospholipids and produces 2-acyl lysophospholipids. Hydrolyzes phosphatidylserine (PS) in the form of liposomes and 1-acyl-2 lysophosphatidylserine (lyso-PS), but not triolein, phosphatidylcholine (PC), phosphatidylethanolamine (PE), phosphatidic acid (PA) or phosphatidylinositol (PI). Isoform 2 hydrolyzes lyso-PS but not PS. Hydrolysis of lyso-PS in peritoneal mast cells activated by receptors for IgE leads to stimulate histamine production.,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,tissue specificity:Widely expressed. Expressed in placenta, prostate and liver. Weakly or not expressed in skin, leukocytes, platelets, colon, spleen, lung, muscle and kidney.,Subcellular Location:
acrosomal membrane,extracellular region,extracellular exosome,Expression:
Brain,Melanoma,Skin,
- Immunohistochemistry analysis of paraffin-embedded human brain, using PLA1A Antibody. The picture on the right is blocked with the synthesized peptide.
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Catalog Number
- Amount:100ul
- Price:225$
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