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PKI β Polyclonal Antibody
Datasheet
Catalog Number:
E20-73776Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human IPKB. AA range:29-78Source:
Polyclonal, RabbitGene Name:
PKIBDilution:
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
- Immunofluorescence analysis of MCF7 cells, using IPKB Antibody. The picture on the right is blocked with the synthesized peptide.
Background:
protein kinase (cAMP-dependent, catalytic) inhibitor beta(PKIB) Homo sapiens This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012],Protein Name:
cAMP-dependent protein kinase inhibitor betaHuman Gene Id:
5570Human Swiss Prot No:
Q9C010Mouse Swiss Prot No:
Q04758Rat Swiss Prot No:
P27775Specificity:
PKI β Polyclonal Antibody detects endogenous levels of PKI β protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
PKIB; PRKACN2; cAMP-dependent protein kinase inhibitor beta; PKI-betaMolecularWeight(Da):
8468Function:
function:Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.,similarity:Belongs to the PKI family.,Subcellular Location:
nucleus,cytoplasm,Expression:
Placenta,
- Immunohistochemistry analysis of paraffin-embedded human brain tissue, using IPKB Antibody. The picture on the right is blocked with the synthesized peptide.
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