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PKAγ cat Polyclonal Antibody
Datasheet
Catalog Number:
E20-73751Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human KAPCG. AA range:1-50Source:
Polyclonal, Rabbit
- Western Blot analysis of COLO205 cells using PKAγ cat Polyclonal Antibody
Gene Name:
PRKACGDilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.Background:
protein kinase cAMP-activated catalytic subunit gamma(PRKACG) Homo sapiens Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit. [provided by RefSeq, Jul 2008],Protein Name:
cAMP-dependent protein kinase catalytic subunit gammaHuman Gene Id:
5568Human Swiss Prot No:
P22612Specificity:
PKAγ cat Polyclonal Antibody detects endogenous levels of PKAγ cat protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
PRKACG; cAMP-dependent protein kinase catalytic subunit gamma; PKA C-gammaMolecularWeight(Da):
40434Observed Band(KD):
40Function:
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activated by cAMP.,function:Phosphorylates a large number of substrates in the cytoplasm and the nucleus.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,subunit:A number of inactive tetrameric holoenzymes are produced by the combination of homo- or heterodimers of the different regulatory subunits associated with two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits.,tissue specificity:Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.,Subcellular Location:
nucleoplasm,cytosol,ciliary base,Expression:
Brain,Testis,
- Western blot analysis of lysates from COLO205 cells, using KAPCG Antibody. The lane on the right is blocked with the synthesized peptide.
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Catalog Number
- Amount:100ul
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