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PinX1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-73732Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human PINX1. AA range:121-170Source:
Polyclonal, RabbitGene Name:
PINX1Dilution:
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.Background:
domain:The TID (telomerase inhibiting domain) domain is sufficient to bind TERT and inhibit its activity.,function:Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.,similarity:Belongs to the PINX1 family.,similarity:Contains 1 G-patch domain.,subcellular location:In nucleoli and at telomere speckles.,subunit:Binds to MCRS1, TERT and TERF1.,tissue specificity:Ubiquitous; expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.,Protein Name:
PIN2/TERF1-interacting telomerase inhibitor 1Human Gene Id:
54984Human Swiss Prot No:
Q96BK5Mouse Swiss Prot No:
Q9CZX5Specificity:
PinX1 Polyclonal Antibody detects endogenous levels of PinX1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
PINX1; LPTL; LPTS; PIN2/TERF1-interacting telomerase inhibitor 1; Liver-related putative tumor suppressor; Pin2-interacting protein X1; Protein 67-11-3; TRF1-interacting protein 1MolecularWeight(Da):
37035Function:
domain:The TID (telomerase inhibiting domain) domain is sufficient to bind TERT and inhibit its activity.,function:Inhibits telomerase activity. May inhibit cell proliferation and act as tumor suppressor.,similarity:Belongs to the PINX1 family.,similarity:Contains 1 G-patch domain.,subcellular location:In nucleoli and at telomere speckles.,subunit:Binds to MCRS1, TERT and TERF1.,tissue specificity:Ubiquitous; expressed at low levels. Not detectable in a number of hepatocarcinoma cell lines.,Subcellular Location:
nuclear chromosome,kinetochore,condensed chromosome kinetochore,nuclear chromosome, telomeric region,nucleus,nucleolus,cytoplasm,mitochondrion,spindle,intracellular membrane-bounded organelle,Expression:
B-cell,Colon,Skin,
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