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PIG-H Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-73725

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human PIGH. AA range:137-186

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    PIGH

  • Dilution:

    Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

  • Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PIGH Antibody. The picture on the right is blocked with the synthesized peptide.

  • Background:

    phosphatidylinositol glycan anchor biosynthesis class H(PIGH) Homo sapiens This gene encodes an endoplasmic reticulum associated protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. The protein encoded by this gene is a subunit of the GPI N-acetylglucosaminyl (GlcNAc) transferase that transfers GlcNAc to phosphatidylinositol (PI) on the cytoplasmic side of the endoplasmic reticulum. [provided by RefSeq, Jul 2008],

  • Protein Name:

    Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

  • Human Gene Id:

    5283

  • Human Swiss Prot No:

    Q14442

  • Mouse Gene Id:

    110417

  • Mouse Swiss Prot No:

    Q5M9N4

  • Specificity:

    PIG-H Polyclonal Antibody detects endogenous levels of PIG-H protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    PIGH; Phosphatidylinositol N-acetylglucosaminyltransferase subunit H; Phosphatidylinositol-glycan biosynthesis class H protein; PIG-H

  • MolecularWeight(Da):

    21081

  • Function:

    catalytic activity:UDP-N-acetyl-D-glucosamine + 1-phosphatidyl-1D-myo-inositol = UDP + 6-(N-acetyl-alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol.,function:Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.,online information:Phosphatidylinositol N-acetylglucosaminyltransferase subunit H,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGH family.,subunit:Associates with PIGA, PIGC, PIGP, PIGQ and DPM2. The latter is not essential for activity.,

  • Subcellular Location:

    glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex,endoplasmic reticulum,endoplasmic reticulum membrane,integral component of membrane,

  • Expression:

    Blood,Lung,Placenta,

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Catalog Number

  • Amount:100ul
  • Price:225$

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