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PGD Polyclonal Antibody
Datasheet
Catalog Number:
E20-73688Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human PGD. AA range:71-120Source:
Polyclonal, Rabbit
- Western Blot analysis of A549 cells using PGD Polyclonal Antibody
Gene Name:
PGDDilution:
IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.Background:
phosphogluconate dehydrogenase(PGD) Homo sapiens 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015],Protein Name:
6-phosphogluconate dehydrogenase decarboxylatingHuman Gene Id:
5226Human Swiss Prot No:
P52209Mouse Gene Id:
110208Mouse Swiss Prot No:
Q9DCD0Rat Gene Id:
1.0036e+008Rat Swiss Prot No:
P85968Specificity:
PGD Polyclonal Antibody detects endogenous levels of PGD protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
PGD; PGDH; 6-phosphogluconate dehydrogenase; decarboxylatingMolecularWeight(Da):
53140Observed Band(KD):
40Function:
catalytic activity:6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH.,pathway:Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.,similarity:Belongs to the 6-phosphogluconate dehydrogenase family.,subunit:Homodimer.,Subcellular Location:
nucleus,cytosol,extracellular exosome,Expression:
Heart,Lungl,
- Immunohistochemical analysis of paraffin-embedded Human colon. 1, Antibody was diluted at 1:100(4° overnight). 2, High-pressure and temperature EDTA, pH8.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).
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Catalog Number
- Amount:100ul
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