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Peroxin 10 Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-73670

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human PEX10. AA range:183-232

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    PEX10

  • Dilution:

    Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

  • Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PEX10 Antibody. The picture on the right is blocked with the synthesized peptide.

  • Background:

    peroxisomal biogenesis factor 10(PEX10) Homo sapiens This gene encodes a protein involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane. Mutations in this gene result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

  • Protein Name:

    Peroxisome biogenesis factor 10

  • Human Gene Id:

    5192

  • Human Swiss Prot No:

    O60683

  • Mouse Swiss Prot No:

    B1AUE5

  • Specificity:

    Peroxin 10 Polyclonal Antibody detects endogenous levels of Peroxin 10 protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    PEX10; RNF69; Peroxisome biogenesis factor 10; Peroxin-10; Peroxisomal biogenesis factor 10; Peroxisome assembly protein 10; RING finger protein 69

  • MolecularWeight(Da):

    37069

  • Observed Band(KD):

    45

  • Function:

    disease:Defects in PEX10 are a cause of adrenoleukodystrophy neonatal (NALD) [MIM:202370]. NALD is a peroxisome biogenesis disorder (PBD) characterized by the accumulation of very long-chain fatty acids, adrenal insufficiency and mental retardation.,disease:Defects in PEX10 are a cause of Zellweger syndrome (ZWS) [MIM:214100]. ZWS is a fatal peroxisome biogenesis disorder characterized by dysmorphic facial features, hepatomegaly, ocular abnormalities, renal cysts, hearing impairment, profound psychomotor retardation, severe hypotonia and neonatal seizures. Death occurs within the first year of life.,disease:Defects in PEX10 are the cause of peroxisome biogenesis disorder complementation group 7 (PBD-CG7) [MIM:602859]; also known as PBD-CGB. PBD refers to a group of peroxisomal disorders arising from a failure of protein import into the peroxisomal membrane or matrix. The PBD group is com

  • Subcellular Location:

    intracellular,peroxisome,peroxisomal membrane,integral component of peroxisomal membrane,

  • Expression:

    Brain,Lung,

  • Western blot analysis of lysates from Jurkat cells, using PEX10 Antibody. The lane on the right is blocked with the synthesized peptide.

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Catalog Number

  • Amount:100ul
  • Price:225$

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Peroxin 10 Polyclonal Antibody | EnoGene Biotech Co. Ltd