You are here: EnoGene Home > Products > Cell Signal Transduction Research Antibodies > PEDF Polyclonal Antibody

PEDF Polyclonal Antibody
Datasheet   

  • Catalog Number:

    E20-73658

  • Amount:

    100ul

  • Price:

    225$

  • Purification:

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen:

    The antiserum was produced against synthesized peptide derived from human PEDF. AA range:258-307

  • Source:

    Polyclonal, Rabbit

  • Gene Name:

    SERPINF1

  • Dilution:

    WB 1:500-2000 Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

  • Immunohistochemistry analysis of PEDF antibody in paraffin-embedded human prostate carcinoma tissue.

  • Background:

    serpin family F member 1(SERPINF1) Homo sapiens This gene encodes a member of the serpin family that does not display the serine protease inhibitory activity shown by many of the other serpin proteins. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells. Mutations in this gene were found in individuals with osteogenesis imperfecta, type VI. [provided by RefSeq, Aug 2016],

  • Protein Name:

    Pigment epithelium-derived factor

  • Human Gene Id:

    5176

  • Human Swiss Prot No:

    P36955

  • Mouse Gene Id:

    20317

  • Mouse Swiss Prot No:

    P97298

  • Specificity:

    PEDF Polyclonal Antibody detects endogenous levels of PEDF protein.

  • Formulation:

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Concentration:

    1 mg/ml

  • Storage Stability:

    -20°C/1 year

  • Other Name:

    SERPINF1; PEDF; PIG35; Pigment epithelium-derived factor; PEDF; Cell proliferation-inducing gene 35 protein; EPC-1; Serpin F1

  • MolecularWeight(Da):

    46342

  • Observed Band(KD):

    46

  • Function:

    developmental stage:Expressed in quiescent cells.,domain:The N-terminal (AA 44-121) exhibits neurite outgrowth-inducing activity. The C-terminal exposed loop (AA 382-418) is essential for serpin activity.,function:Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.,PTM:The N-terminus is blocked. Extracellular phosphorylation enhances antiangiogenic activity.,similarity:Belongs to the serpin family.,subcellular location:Enriched in stage I melanosomes.,tissue specificity:Retinal pigment epithelial cells and blood plasma.,

  • Subcellular Location:

    extracellular region,basement membrane,extracellular space,extracellular matrix,melanosome,axon hillock,perinuclear region of cytoplasm,extracellular exosome,

  • Expression:

    Fetal eye,Fetal lung fibroblast,Liver,Muscle,Plasma,

  • Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night

Add to Cart

Related Products

PTEN (Phospho-Ser380) Antibody
PTEN (Phospho-Ser380) Antibody Datasheet  

  • Catalog Number:

    E011009-1

  • Amount:

    50μg/50μl

  • Reactivity:

    Human, Mouse, Rat

  • Applications:

    IHC: 1:50~1:100

  • Swiss-Prot No.:

    P60484

  • Price:

    145$
  • Add to Cart
PTEN (Phospho-Ser380) Antibody
PTEN (Phospho-Ser380) Antibody Datasheet  

  • Catalog Number:

    E011009-2

  • Amount:

    100μg/100μl

  • Reactivity:

    Human, Mouse, Rat

  • Applications:

    IHC: 1:50~1:100

  • Swiss-Prot No.:

    P60484

  • Price:

    225$
  • Add to Cart
NFκB-p65 (Phospho-Ser468) Antibody
NFκB-p65 (Phospho-Ser468) Antibody Datasheet  

  • Catalog Number:

    E011013-1

  • Amount:

    50μg/50μl

  • Reactivity:

    Human, Mouse, Rat

  • Applications:

    WB: 1:500~1:1000 IF:1:100~1:200

  • Swiss-Prot No.:

    Q04206

  • Price:

    145$
  • Add to Cart
NFκB-p65 (Phospho-Ser468) Antibody
NFκB-p65 (Phospho-Ser468) Antibody Datasheet  

  • Catalog Number:

    E011013-2

  • Amount:

    100μg/100μl

  • Reactivity:

    Human, Mouse, Rat

  • Applications:

    WB: 1:500~1:1000 IF:1:100~1:200

  • Swiss-Prot No.:

    Q04206

  • Price:

    225$
  • Add to Cart
Rel (Phospho-Ser503) Antibody
Rel (Phospho-Ser503) Antibody Datasheet  

  • Catalog Number:

    E011020-1

  • Amount:

    50μg/50μl

  • Reactivity:

    Human

  • Applications:

    IF:1:100~1:200

  • Swiss-Prot No.:

    Q04864

  • Price:

    145$
  • Add to Cart

Catalog Number

  • Amount:100ul
  • Price:225$

Add to Cart

AbPromise

Contact us

PEDF Polyclonal Antibody | EnoGene Biotech Co. Ltd