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Cell Signal Transduction Research Antibodies
PDLIM5 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight64002 Da
Protein NamePDZ and LIM domain protein 5
Human Gene Id10611
Human Swiss Prot NoQ96HC4
Mouse Swiss Prot NoQ8CI51
SpecificityPDLIM5 Polyclonal Antibody detects endogenous levels of PDLIM5 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NamePDLIM5; ENH; L9; PDZ and LIM domain protein 5; Enigma homolog; Enigma-like PDZ and LIM domains protein
Observed Band(KD)64
Functioncaution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,disease:May play a role in genetic susceptibility to schizophrenia. PDLIM5 is commonly increased in the brain of patients with bipolar disorder, schizophrenia, and major depression.,function:May play an important role in the heart development by scaffolding PKC to the Z-disk region.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 3 LIM zinc-binding domains.,subunit:Interacts with various PKC isoforms through the LIM domains. Interacts with actin and alpha-actinin through the PDZ domain.,tissue specificity:Heart and skeletal muscle specific.,
Subcellular Locationcytoplasm,cytosol,cell-cell adherens junction,postsynaptic density,actin cytoskeleton,membrane,neuron projection,postsynaptic membrane,
ExpressionBrain,Epithelium,Liver,Placenta,Platelet,Skeletal muscle,Skin,
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human PDLIM5. AA range:208-257
Gene NamePDLIM5
DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
BackgroundPDZ and LIM domain 5(PDLIM5) Homo sapiens This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012],
Conjugated Antibody
This product is also available conjugated. Format: E20-73647-Conjugate. Price: $485 / Size: 100μl.
E20-73647-FITC$485 / 100μlE20-73647-Biotin$485 / 100μlE20-73647-HRP$485 / 100μlE20-73647-AP$485 / 100μlE20-73647-AF350$485 / 100μlE20-73647-AF405M$485 / 100μlE20-73647-AF488$485 / 100μlE20-73647-AF514$485 / 100μlE20-73647-AF532$485 / 100μlE20-73647-AF555$485 / 100μlE20-73647-AF568$485 / 100μlE20-73647-AF405S$485 / 100μlE20-73647-AF405L$485 / 100μlE20-73647-AF546$485 / 100μlE20-73647-AF594$485 / 100μlE20-73647-AF610$485 / 100μlE20-73647-AF635$485 / 100μlE20-73647-AF647$485 / 100μlE20-73647-AF680$485 / 100μlE20-73647-AF700$485 / 100μlE20-73647-AF750$485 / 100μlE20-73647-AF790$485 / 100μlE20-73647-APC$485 / 100μlE20-73647-PE$485 / 100μlE20-73647-Cy3$485 / 100μlE20-73647-Cy5$485 / 100μlE20-73647-Cy5.5$485 / 100μlE20-73647-Cy7$485 / 100μlE20-73647-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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