PDE10A Polyclonal Antibody

Name: PDE10A Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-73627
Price: 225 USD
Availability: InStock

E20-73627Cite ID: EN0053760Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (1)Documents

Product Information

Molecular Weight88412Da

Protein NamecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

Human Gene Id10846

Human Swiss Prot NoQ9Y233

Mouse Swiss Prot NoQ8CA95

Rat Gene Id63885

Rat Swiss Prot NoQ9QYJ6

SpecificityPDE10A Polyclonal Antibody detects endogenous levels of PDE10A protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NamePDE10A; cAMP and cAMP-inhibited cGMP 3'; 5'-cyclic phosphodiesterase 10A

Observed Band(KD)75

Functionalternative products:Isoforms differ in their N-terminal region,catalytic activity:Guanosine 3',5'-cyclic phosphate + H(2)O = guanosine 5'-phosphate.,catalytic activity:Nucleoside 3',5'-cyclic phosphate + H(2)O = nucleoside 5'-phosphate.,cofactor:Binds 1 magnesium ion.,cofactor:Binds 1 zinc ion.,domain:Composed of a C-terminal catalytic domain containing two divalent metal sites and an N-terminal regulatory domain which contains one cyclic nucleotide-binding region.,domain:The tandem GAF domains bind cAMP, and regulate enzyme activity. The binding of cAMP stimulates enzyme activity.,enzyme regulation:Inhibited by dipyridamole and moderately by IBMX. cAMP acts as an allosteric activator.,function:Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient w

Subcellular Locationcytosol,membrane,perikaryon,

ExpressionColon,Fetal brain,Fetal lung,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human PDE10A. AA range:21-70

Gene NamePDE10A

DilutionWestern Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Backgroundphosphodiesterase 10A(PDE10A) Homo sapiens The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2011],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-73627-Conjugate. Price: $485 / Size: 100μl.

E20-73627-FITC$485 / 100μlE20-73627-Biotin$485 / 100μlE20-73627-HRP$485 / 100μlE20-73627-AP$485 / 100μlE20-73627-AF350$485 / 100μlE20-73627-AF405M$485 / 100μlE20-73627-AF488$485 / 100μlE20-73627-AF514$485 / 100μlE20-73627-AF532$485 / 100μlE20-73627-AF555$485 / 100μlE20-73627-AF568$485 / 100μlE20-73627-AF405S$485 / 100μlE20-73627-AF405L$485 / 100μlE20-73627-AF546$485 / 100μlE20-73627-AF594$485 / 100μlE20-73627-AF610$485 / 100μlE20-73627-AF635$485 / 100μlE20-73627-AF647$485 / 100μlE20-73627-AF680$485 / 100μlE20-73627-AF700$485 / 100μlE20-73627-AF750$485 / 100μlE20-73627-AF790$485 / 100μlE20-73627-APC$485 / 100μlE20-73627-PE$485 / 100μlE20-73627-Cy3$485 / 100μlE20-73627-Cy5$485 / 100μlE20-73627-Cy5.5$485 / 100μlE20-73627-Cy7$485 / 100μlE20-73627-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.