P-cadherin Polyclonal Antibody

Name: P-cadherin Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-73614
Price: 225 USD
Availability: InStock

E20-73614Cite ID: EN0053747Datasheet COA MSDS

ReactivityHuman;Rat;Mouse;

ApplicationsWB;IHC-p;IF(paraffin section);ELISA

SourcePolyclonal, Rabbit,IgG

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human CDH3. AA range:51-100

Gene NameCDH3

DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Product Information

Protein NameCadherin-3

Human Gene Id1001

Human Swiss Prot NoP22223

Mouse Swiss Prot NoP10287

SpecificityP-cadherin Polyclonal Antibody detects endogenous levels of P-cadherin protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameCDH3; CDHP; Cadherin-3; Placental cadherin; P-cadherin

Observed Band(KD)86

Functiondisease:Defects in CDH3 are the cause of ectodermal dysplasia with ectrodactyly and macular dystrophy (EEM) [MIM:225280]; also known as EEM syndrome, Albrectsen-Svendsen syndrome or Ohdo-Hirayama-Terawaki syndrome. Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. EEM is an autosomal recessive condition characterized by features of ectodermal dysplasia such as sparse eyebrows and scalp hair, and selective tooth agenesis associated with macular dystrophy and ectrodactyly.,disease:Defects in CDH3 are the cause of hypotrichosis with juvenile macular dystrophy (HJMD) [MIM:601553]. HJMD is a rare autosomal recessive disorder characterized by early hair loss heralding severe degenerative changes of the retinal macula and culminating in blindness during the second to third decade of life.,function:Cadherins are calc

Subcellular LocationCell membrane; Single-pass type I membrane protein.

ExpressionExpressed in some normal epithelial tissues and in some carcinoma cell lines.

BackgroundThis gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). [provided by RefSeq, Nov 2015],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-73614-Conjugate. Price: $485 / Size: 100μl.

E20-73614-FITC$485 / 100μlE20-73614-Biotin$485 / 100μlE20-73614-HRP$485 / 100μlE20-73614-AP$485 / 100μlE20-73614-AF350$485 / 100μlE20-73614-AF405M$485 / 100μlE20-73614-AF488$485 / 100μlE20-73614-AF514$485 / 100μlE20-73614-AF532$485 / 100μlE20-73614-AF555$485 / 100μlE20-73614-AF568$485 / 100μlE20-73614-AF405S$485 / 100μlE20-73614-AF405L$485 / 100μlE20-73614-AF546$485 / 100μlE20-73614-AF594$485 / 100μlE20-73614-AF610$485 / 100μlE20-73614-AF635$485 / 100μlE20-73614-AF647$485 / 100μlE20-73614-AF680$485 / 100μlE20-73614-AF700$485 / 100μlE20-73614-AF750$485 / 100μlE20-73614-AF790$485 / 100μlE20-73614-APC$485 / 100μlE20-73614-PE$485 / 100μlE20-73614-Cy3$485 / 100μlE20-73614-Cy5$485 / 100μlE20-73614-Cy5.5$485 / 100μlE20-73614-Cy7$485 / 100μlE20-73614-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.