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Pax-1 Polyclonal Antibody
Datasheet
Catalog Number:
E20-73599Amount:
100ulPrice:
225$Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.Immunogen:
The antiserum was produced against synthesized peptide derived from human Pax-1. AA range:318-367Source:
Polyclonal, Rabbit
- Immunohistochemistry analysis of Pax-1 antibody in paraffin-embedded human heart tissue.
Gene Name:
PAX1Dilution:
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.Background:
paired box 1(PAX1) Homo sapiens This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. This gene plays a role in pattern formation during embryogenesis and may be essential for development of the vertebral column. This gene is silenced by methylation in ovarian and cervical cancers and may be a tumor suppressor gene. Mutations in this gene are also associated with vertebral malformations. [provided by RefSeq, Mar 2012],Protein Name:
Paired box protein Pax-1Human Gene Id:
5075Human Swiss Prot No:
P15863Mouse Swiss Prot No:
P09084Specificity:
Pax-1 Polyclonal Antibody detects endogenous levels of Pax-1 protein.Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Concentration:
1 mg/mlStorage Stability:
-20°C/1 yearOther Name:
PAX1; HUP48; Paired box protein Pax-1; HuP48MolecularWeight(Da):
46295Observed Band(KD):
36Function:
function:This protein is a transcriptional activator. It may play a role in the formation of segmented structures of the embryo. May play an important role in the normal development of the vertebral column.,similarity:Contains 1 paired domain.,Subcellular Location:
nucleus,
- Western Blot analysis of 293T cells using Pax-1 Polyclonal Antibody diluted at 1:500 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
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