p70 S6 kinase α Polyclonal Antibody

Name: p70 S6 kinase α Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-73549
Price: 225 USD
Availability: InStock

E20-73549Cite ID: EN0053682Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight59140Da

Protein NameRibosomal protein S6 kinase beta-1

Human Gene Id6198

Human Swiss Prot NoP23443

Mouse Gene Id72508

Mouse Swiss Prot NoQ8BSK8

Rat Gene Id83840

Rat Swiss Prot NoP67999

Specificityp70 S6 kinase α Polyclonal Antibody detects endogenous levels of p70 S6 kinase α protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameRPS6KB1; STK14A; Ribosomal protein S6 kinase beta-1; S6K-beta-1; S6K1; 70 kDa ribosomal protein S6 kinase 1; P70S6K1; p70-S6K 1; Ribosomal protein S6 kinase I; Serine/threonine-protein kinase 14A; p70 ribosomal S6 kinase alpha; p70 S6 kinas

Observed Band(KD)60

Functioncatalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activation by serine/threonine phosphorylation and protein kinase C, inactivated by type 2A phosphatase.,function:Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with PPP1R9A/neurabin-1.,tissue specificity:Widely expressed.,

Subcellular LocationCell junction, synapse, synaptosome . Mitochondrion outer membrane. Mitochondrion. Colocalizes with URI1 at mitochondrion.; [Isoform Alpha I]: Nucleus. Cytoplasm.; [Isoform Alpha II]: Cytoplasm.

ExpressionWidely expressed.

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human p70 S6 Kinase. AA range:195-244

Gene NameRPS6KB1

DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Backgroundribosomal protein S6 kinase B1(RPS6KB1) Homo sapiens This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-73549-Conjugate. Price: $485 / Size: 100μl.

E20-73549-FITC$485 / 100μlE20-73549-Biotin$485 / 100μlE20-73549-HRP$485 / 100μlE20-73549-AP$485 / 100μlE20-73549-AF350$485 / 100μlE20-73549-AF405M$485 / 100μlE20-73549-AF488$485 / 100μlE20-73549-AF514$485 / 100μlE20-73549-AF532$485 / 100μlE20-73549-AF555$485 / 100μlE20-73549-AF568$485 / 100μlE20-73549-AF405S$485 / 100μlE20-73549-AF405L$485 / 100μlE20-73549-AF546$485 / 100μlE20-73549-AF594$485 / 100μlE20-73549-AF610$485 / 100μlE20-73549-AF635$485 / 100μlE20-73549-AF647$485 / 100μlE20-73549-AF680$485 / 100μlE20-73549-AF700$485 / 100μlE20-73549-AF750$485 / 100μlE20-73549-AF790$485 / 100μlE20-73549-APC$485 / 100μlE20-73549-PE$485 / 100μlE20-73549-Cy3$485 / 100μlE20-73549-Cy5$485 / 100μlE20-73549-Cy5.5$485 / 100μlE20-73549-Cy7$485 / 100μlE20-73549-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.