p68 RNA Helicase Polyclonal Antibody

Name: p68 RNA Helicase Polyclonal Antibody
Brand: EnoGene Biotech Co. Ltd
SKU: E20-73548
Price: 225 USD
Availability: InStock

E20-73548Cite ID: EN0053681Datasheet COA MSDS

SourcePolyclonal, Rabbit

$225/ 100ul

Quantity

Total: $225

Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.

OverviewImages & Data (2)Documents

Product Information

Molecular Weight69148Da

Protein NameProbable ATP-dependent RNA helicase DDX5

Human Gene Id1655

Human Swiss Prot NoP17844

Mouse Swiss Prot NoQ61656

Specificityp68 RNA Helicase Polyclonal Antibody detects endogenous levels of p68 RNA Helicase protein.

FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration1 mg/ml

Storage Stability-20°C/1 year

Other NameDDX5; G17P1; HELR; HLR1; Probable ATP-dependent RNA helicase DDX5; DEAD box protein 5; RNA helicase p68

Observed Band(KD)70

Functionfunction:RNA-dependent ATPase activity. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. May be involved in pre-mRNA splicing.,PTM:Arg-502 is dimethylated, probably to asymmetric dimethylarginine.,similarity:Belongs to the DEAD box helicase family.,similarity:Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Identified in the spliceosome C complex, at least composed of AQR, C19orf29, CDC40, CDC5L, CRNKL1, DDX23, DDX41, DDX48, DDX5, DGCR14, DHX35, DHX38, DHX8, EFTUD2, FRG1, GPATC1, HNRPA1, HNRPA2B1, HNRPA3, HNRPC, HNRPF, HNRPH1, HNRPK, HNRPM, HNRPR, HNRPU, KIAA1160, KIAA1604, LSM2, LSM3, MAGOH, MORG1, PABPC1, PLRG1, PNN, PPIE, PPIL1, PPIL3, PPWD1, PRPF19, PRPF4B, PRPF6, PRPF8, RALY, RBM22, RBM8A, RBMX, SART1, SF3A1, SF3A2, SF3A3, SF3B1, SF3B2, SF3

Subcellular LocationNucleus . Nucleus, nucleolus . Cytoplasm . During the G0 phase, predominantly located in the nucleus. Cytoplasmic levels increase during the G1/S phase. During the M phase, located at the vicinity of the condensed chromosomes. At G1, localizes in the cytoplasm. .

ExpressionAorta endothelial cell,Epithelium,Human esophagus tumor,Muscle,

PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

ImmunogenThe antiserum was produced against synthesized peptide derived from human DDX5/DEAD-box Protein 5. AA range:565-614

Gene NameDDX5

DilutionWestern Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

BackgroundDEAD-box helicase 5(DDX5) Homo sapiens DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a RNA-dependent ATPase, and also a proliferation-associated nuclear antigen, specifically reacting with the simian virus 40 tumor antigen. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],

📄Datasheet
Full product datasheet (PDF)✅Certificate of Analysis
Lot-specific COA (generated from product data)🧪MSDS
Material safety data sheet (generated)

Conjugated Antibody

This product is also available conjugated. Format: E20-73548-Conjugate. Price: $485 / Size: 100μl.

E20-73548-FITC$485 / 100μlE20-73548-Biotin$485 / 100μlE20-73548-HRP$485 / 100μlE20-73548-AP$485 / 100μlE20-73548-AF350$485 / 100μlE20-73548-AF405M$485 / 100μlE20-73548-AF488$485 / 100μlE20-73548-AF514$485 / 100μlE20-73548-AF532$485 / 100μlE20-73548-AF555$485 / 100μlE20-73548-AF568$485 / 100μlE20-73548-AF405S$485 / 100μlE20-73548-AF405L$485 / 100μlE20-73548-AF546$485 / 100μlE20-73548-AF594$485 / 100μlE20-73548-AF610$485 / 100μlE20-73548-AF635$485 / 100μlE20-73548-AF647$485 / 100μlE20-73548-AF680$485 / 100μlE20-73548-AF700$485 / 100μlE20-73548-AF750$485 / 100μlE20-73548-AF790$485 / 100μlE20-73548-APC$485 / 100μlE20-73548-PE$485 / 100μlE20-73548-Cy3$485 / 100μlE20-73548-Cy5$485 / 100μlE20-73548-Cy5.5$485 / 100μlE20-73548-Cy7$485 / 100μlE20-73548-PE-Cy5$485 / 100μl

Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.