World supplier of antibodies, antigens and kits since 2007
Cell Signal Transduction Research Antibodies
p47-phox Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight44683Da
Protein NameNeutrophil cytosol factor 1
Human Gene Id653361
Human Swiss Prot NoP14598
Mouse Swiss Prot NoQ09014
Specificityp47-phox Polyclonal Antibody detects endogenous levels of p47-phox protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameNCF1; NOXO2; SH3PXD1A; Neutrophil cytosol factor 1; NCF-1; 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-47K; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox-organizing protein 2; SH3
Observed Band(KD)44
Functiondisease:Defects in NCF1 are the cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 1 (CGD1) [MIM:233700]. Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.,function:NCF2, NCF1, and a membrane bound cytochrome b558 are required for activation of the latent NADPH oxidase (necessary for superoxide production).,online information:NCF1 deficiency database,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 2 SH3 domains.,subunit:Interacts with NOXA1.,
Subcellular LocationCytoplasm, cytosol . Membrane ; Peripheral membrane protein ; Cytoplasmic side .
ExpressionDetected in peripheral blood monocytes and neutrophils (at protein level).
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human p47 phox. AA range:281-330
Gene NameNCF1
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Backgroundneutrophil cytosolic factor 1(NCF1) Homo sapiens The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-73519-Conjugate. Price: $485 / Size: 100μl.
E20-73519-FITC$485 / 100μlE20-73519-Biotin$485 / 100μlE20-73519-HRP$485 / 100μlE20-73519-AP$485 / 100μlE20-73519-AF350$485 / 100μlE20-73519-AF405M$485 / 100μlE20-73519-AF488$485 / 100μlE20-73519-AF514$485 / 100μlE20-73519-AF532$485 / 100μlE20-73519-AF555$485 / 100μlE20-73519-AF568$485 / 100μlE20-73519-AF405S$485 / 100μlE20-73519-AF405L$485 / 100μlE20-73519-AF546$485 / 100μlE20-73519-AF594$485 / 100μlE20-73519-AF610$485 / 100μlE20-73519-AF635$485 / 100μlE20-73519-AF647$485 / 100μlE20-73519-AF680$485 / 100μlE20-73519-AF700$485 / 100μlE20-73519-AF750$485 / 100μlE20-73519-AF790$485 / 100μlE20-73519-APC$485 / 100μlE20-73519-PE$485 / 100μlE20-73519-Cy3$485 / 100μlE20-73519-Cy5$485 / 100μlE20-73519-Cy5.5$485 / 100μlE20-73519-Cy7$485 / 100μlE20-73519-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
Categories by research area
Categories by product type
- Antibodies
- Tag antibodies
- Internal control antibodies
- Pathological (Immunohistochemistry, IHC) antibodies
- Cell Signal Transduction Research Antibodies
- Secondary Antibody
- Antibody Sampler Kits
- Recombinant Proteins
- Fluorescence Reagents
- Signal Inhibitors and Activators
- Transfection Reagent
- Cell biology kits