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Cell Signal Transduction Research Antibodies
P2Y4 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight40963Da
Protein NameP2Y purinoceptor 4
Human Gene Id5030
Human Swiss Prot NoP51582
Mouse Gene Id57385
Mouse Swiss Prot NoQ9JJS7
Rat Gene Id63843
Rat Swiss Prot NoO35811
SpecificityP2Y4 Polyclonal Antibody detects endogenous levels of P2Y4 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameP2RY4; NRU; P2Y purinoceptor 4; P2Y4; P2P; Uridine nucleotide receptor; UNR
Observed Band(KD)41
Functionfunction:Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP.,PTM:Phosphorylation of Ser-333 and Ser-334 is a key step in agonist-dependent desensitization and loss of surface P2RY4. This phosphorylation does not involve PKC, nor other calcium activated kinases.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Pancreas.,
Subcellular LocationCell membrane; Multi-pass membrane protein.
ExpressionPancreas.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human P2RY4. AA range:159-208
Gene NameP2RY4
DilutionWestern Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundpyrimidinergic receptor P2Y4(P2RY4) Homo sapiens The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-73506-Conjugate. Price: $485 / Size: 100μl.
E20-73506-FITC$485 / 100μlE20-73506-Biotin$485 / 100μlE20-73506-HRP$485 / 100μlE20-73506-AP$485 / 100μlE20-73506-AF350$485 / 100μlE20-73506-AF405M$485 / 100μlE20-73506-AF488$485 / 100μlE20-73506-AF514$485 / 100μlE20-73506-AF532$485 / 100μlE20-73506-AF555$485 / 100μlE20-73506-AF568$485 / 100μlE20-73506-AF405S$485 / 100μlE20-73506-AF405L$485 / 100μlE20-73506-AF546$485 / 100μlE20-73506-AF594$485 / 100μlE20-73506-AF610$485 / 100μlE20-73506-AF635$485 / 100μlE20-73506-AF647$485 / 100μlE20-73506-AF680$485 / 100μlE20-73506-AF700$485 / 100μlE20-73506-AF750$485 / 100μlE20-73506-AF790$485 / 100μlE20-73506-APC$485 / 100μlE20-73506-PE$485 / 100μlE20-73506-Cy3$485 / 100μlE20-73506-Cy5$485 / 100μlE20-73506-Cy5.5$485 / 100μlE20-73506-Cy7$485 / 100μlE20-73506-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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