Product Information
Molecular Weight40635Da
Protein NameP2Y purinoceptor 8
Human Gene Id286530
Human Swiss Prot NoQ86VZ1
SpecificityP2RY8 Polyclonal Antibody detects endogenous levels of P2RY8 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameP2RY8; P2Y purinoceptor 8; P2Y8
Observed Band(KD)41
Functionfunction:Probable receptor for purines coupled to G-proteins.,induction:Down-regulated during granulocytic regulation.,miscellaneous:The gene encoding for this protein is located in the pseudoautosomal region 1 (PAR1) of X and Y chromosomes.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Barely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.,
Subcellular LocationCell membrane; Multi-pass membrane protein.
ExpressionBarely detectable in normal blood leukocytes. Weaker expression was seen in heart, kidney and lung. Not detected in brain.
Backgroundpurinergic receptor P2Y8(P2RY8) Homo sapiens The protein encoded by this gene belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. This gene is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y. [provided by RefSeq, Jul 2008],