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Cell Signal Transduction Research Antibodies
OY-TES-1 Polyclonal Antibody
Polyclonal, Rabbit
$225/ 100ul
QuantityTotal: $225
Ship worldwide. Contact order@enogene.com for ordering and bulk pricing or contact your local distributor.
Product Information
Molecular Weight61359Da
Protein NameAcrosin-binding protein
Human Gene Id84519
Human Swiss Prot NoQ8NEB7
Mouse Swiss Prot NoQ3V140
SpecificityOY-TES-1 Polyclonal Antibody detects endogenous levels of OY-TES-1 protein.
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Concentration1 mg/ml
Storage Stability-20°C/1 year
Other NameACRBP; Acrosin-binding protein; Cancer/testis antigen 23; CT23; Cancer/testis antigen OY-TES-1; Proacrosin-binding protein sp32
Observed Band(KD)61
Functionfunction:May be involved in packaging and condensation of the acrosin zymogen in the acrosomal matrix via its association with proacrosin.,PTM:Phosphorylated on Tyr residues in capacitated sperm.,PTM:The N-terminus is blocked.,subcellular location:Colocalizes with proacrosin in the acrosome of sperm.,subunit:Binds proacrosin.,tissue specificity:Expression restricted to testis in normal tissue. Expressed in a wide spectrum of cancers, including bladder, breast, liver, lung and colon cancers.,
Subcellular LocationSecreted . Cytoplasmic vesicle, secretory vesicle, acrosome .
ExpressionExpression restricted to testis in normal tissue. Expressed in a wide spectrum of cancers, including bladder, breast, liver, lung and colon cancers.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ImmunogenThe antiserum was produced against synthesized peptide derived from human ACRBP. AA range:181-230
Gene NameACRBP
DilutionWestern Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Backgroundacrosin binding protein(ACRBP) Homo sapiens The protein encoded by this gene is similar to proacrosin binding protein sp32 precursor found in mouse, guinea pig, and pig. This protein is located in the sperm acrosome and is thought to function as a binding protein to proacrosin for packaging and condensation of the acrosin zymogen in the acrosomal matrix. This protein is a member of the cancer/testis family of antigens and it is found to be immunogenic. In normal tissues, this mRNA is expressed only in testis, whereas it is detected in a range of different tumor types such as bladder, breast, lung, liver, and colon. [provided by RefSeq, Jul 2008],
Conjugated Antibody
This product is also available conjugated. Format: E20-73483-Conjugate. Price: $485 / Size: 100μl.
E20-73483-FITC$485 / 100μlE20-73483-Biotin$485 / 100μlE20-73483-HRP$485 / 100μlE20-73483-AP$485 / 100μlE20-73483-AF350$485 / 100μlE20-73483-AF405M$485 / 100μlE20-73483-AF488$485 / 100μlE20-73483-AF514$485 / 100μlE20-73483-AF532$485 / 100μlE20-73483-AF555$485 / 100μlE20-73483-AF568$485 / 100μlE20-73483-AF405S$485 / 100μlE20-73483-AF405L$485 / 100μlE20-73483-AF546$485 / 100μlE20-73483-AF594$485 / 100μlE20-73483-AF610$485 / 100μlE20-73483-AF635$485 / 100μlE20-73483-AF647$485 / 100μlE20-73483-AF680$485 / 100μlE20-73483-AF700$485 / 100μlE20-73483-AF750$485 / 100μlE20-73483-AF790$485 / 100μlE20-73483-APC$485 / 100μlE20-73483-PE$485 / 100μlE20-73483-Cy3$485 / 100μlE20-73483-Cy5$485 / 100μlE20-73483-Cy5.5$485 / 100μlE20-73483-Cy7$485 / 100μlE20-73483-PE-Cy5$485 / 100μl
Contact order@enogene.com to order conjugated formats. Magnetic Beads (1-30μm) conjugation is also available.
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